Alexa Fluor® 488 大鼠抗小鼠 CD19 抗体 (1D3) 是来自STARTER品牌的高品质产品,适用于科研实验领域。
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CD19 is a 95 kDa type I transmembrane glycoprotein that belongs to the immunoglobulin superfamily and is expressed on the surface of B lymphocytes and follicular dendritic cells. It plays a crucial role in B cell activation and humoral immune responses by forming a complex with CD21, CD81, and CD225. This complex reduces the threshold for B cell receptor (BCR) activation, enhancing downstream signaling pathways and facilitating B cell responses to antigens. CD19 is also a biomarker for B cell development and lymphoma diagnosis, and it is targeted in immunotherapies for diseases like leukemia.
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
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