Hot Sale Polypeptide Hormone Follistatin315 1mg/Vial for Muscle Building
Basic Info
Product Name:Follistatin 315
Purity:99.0%
M.F.: C33H57N11O9
M.W.: 751.9
Port: Guangzhou, China
Production Capacity:4000kg/Month
Payment Terms: T/T, Western Union, Money Gram, Bitcoin
Model NO.: Qualified
Customized: Customized
Suitable for: Adult, Body Builders
Purity: >99%
Payment Terms: Western Union, Bitcoin, Money Gram, Bank Transfer
Storage: Exposure to Direct Sunlight Must Be Avoided
Specification: GMP, USP, ISO9001
HS Code: 3001901000
Powder: Yes
Certification: GMP, HSE, ISO 9001, USP, BP, Ukas
State: Solid
Appearance: White Powder
Shipment Way: DHL, TNT, UPS, EMS, Hongkong Post
Quality: Wonderful
Transport Package: Disguised and Discreet
Origin: China
Hot Sale Polypeptide Hormone Follistatin315 1mg/Vial for Muscle Building
Product Description
Hot Sale Polypeptide Hormone Follistatin315 1mg/Vial for Muscle Building
Hot Sale Polypeptide Hormone Follistatin315 1mg/Vial for Muscle Building
Quick Details:
Product Name: Follistatin 315
Specification: 1mg/vial
Purity (by HPLC) :≥98.0%
Appearance : White powder
Usuage: Follistatin is fascinating protein that can increase muscle mass beyond natural potential by suppressing myostatin. Scientists first identified follistatin while examining porcine (re: pig) follicular fluid in the ovaries.
Description:
Follistatin is a secreted glycoprotein that was first identified as a folliclestimulating hormone inhibiting substance in ovarian follicular fluid.Human Follistatin cDNA encodes a 344 amino acid protein with a 29 aa signal sequence, an Nterminal atypical TGF binding domain, three Follistatin domains that contain EGF like and kazallike motifs, and a highly acidic Cterminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors.
It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH. In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin 315 is a 34.7 kDa protein containing amino acids 30-344 of the FST-344 protein.
Follistatin also known as activin-binding protein is a protein that in humans is encoded by the FST gene.Follistatin is an autocrine glycoprotein that is expressed in nearly all tissues of higher animals.Its primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a particular focus on activin, a paracrine hormone.
Applications:
Follistatin 315 is a naturally occurring human peptide and a potent inhibitor of myostatin. Myostatin encourages the degradation of myotubes therefore inhibition of myostatin will ultimately result in increased muscle mass by preventing degradation.Follistatin is being studied for its role in regulation of muscle growth, as an antagonist to myostatin.
Either by genetic elimination or by increasing the amount of follistatin, resulted in greatly increased muscle mass.In 2009, research with macaque monkeys demonstrated that regulating follistatin via gene therapy also resulted in muscle growth and increases in strength.A study has also shown that increased levels of follistatin, by leading to increased muscle mass of certain core muscular groups, can increase life expectancy in cases of spinal muscular atrophy in animal models.
Follistatin 315 primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a particular focus on activin, a paracrine hormone.