P6258-5μg
Recombinant Rat IL-2, Liquid
5μg
464.00元
Species
Gene ID
Accession
Source
Length
MW
Tag
Rat
116562
P17108
E. coli
135aa
15.5kDa
－
Name
Recombinant Rat IL-2, Liquid (Recombinant Rat Interleukin-2, Liquid; rRtIL-2, Liquid)；重组大鼠白细胞介素2，液体
Synonyms
aldesleukin; Aldesleukin; IL-2lymphokine; interleukin 2; interleukin-2; involved in regulation of T-cell clonal expansion; T cell growth factor; T-cell growth factor; TCGF
Purity
>97% by SDS-PAGE and HPLC analyses.
Biological Activity
Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.2ng/ml, corresponding to a specific activity of >5.0×106IU/mg.
Physical Appearance
Sterile Colorless liquid.
Formulation
A 0.2μm filtered concentrated sterile solution in 10mM sodium citrate, pH4.0, 30% glycerol.
Endotoxin
Less than 1EU/μg of rRtIL-2, Liquid as determined by LAL method.
Background
IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. IL-2/IL-2R signaling is required for Tcell proliferation and other fundamental functions which are essential for the immune response. The receptor for IL-2 consists of three subunits (55kDa IL2Rα, 75kDa IL2Rβ, 64kDa common gamma chain γc/IL2Rγ) that are present on the cell surface in varying preformed complexes. Recombinant rat IL-2 is a 15.3kDa protein containing 134 amino acid residues and it shares about 82%, 66%, 66%, 60% and 54% amino acid sequence identity with mouse, human, rhesus macaque, pig and equus caballus IL-2, respectively.
Amino Acid Sequence
APTSSPAKET QQHLEQLLLD LQVLLRGIDN YKNLKLPMML TFKFYLPKQA TELKHLQCLE NELGALQRVL DLTQSKSFHL EDAGNFISNI RVTVVKLKGS ENKFECQFDD EPATVVEFLR RWIAICQSII STMTQ
包装清单:
P6258-5μg
Recombinant Rat IL-2, Liquid
5μg
P6258-20μg
Recombinant Rat IL-2, Liquid
20μg
P6258-100μg
Recombinant Rat IL-2, Liquid
100μg
P6258-1mg
Recombinant Rat IL-2, Liquid
1mg
保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。