Anti-ATF4 antibodyCat. No. JC120294
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-ATF4 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human ATF4
Reactivity Human, Mouse, Rat
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-ATF4 antibodyTarget information
Symbol ATF4
Full name activating transcription factor 4
Synonyms CREB2; TXREB; CREB-2; TAXREB67
Swissprot P18848
Target Background
This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain.
Anti-ATF4 antibodyApplications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 50-200 Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 50-200
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