Tretinoin;All-trans Retinoic Acid

Tretinoin;All-trans Retinoic Acid,Tretinoin;All-trans Retinoic Acid
  • Tretinoin;All-trans Retinoic Acid,Tretinoin;All-trans Retinoic Acid
  • 产品价格:¥252
  • 中文名称:Tretinoin;All-trans Retinoic Acid
  • 英文名称:Tretinoin;All-trans Retinoic Acid
  • CAS:
  • 发布时间:2020/6/2 10:24:02
委托采购
联系方式
  • 爱必信(上海) 生物科技有限公司 | 点击这里给我发消息
  • 会员等级: 企业会员 1年 | 上海市浦东新区新浩路58号18号楼
  • 产品描述
  • 公司简介

产品属性:

  • 产品名称: Tretinoin;All-trans Retinoic Acid
  • 产品英文名称: Tretinoin;All-trans Retinoic Acid
  • 包装价格: 10mg/252RMB;200mg/674RMB
  • 产品类别: 激动剂抑制剂
发布时间: 2020/6/2 10:24:02 产品名称: Tretinoin;All-trans Retinoic Acid 产品英文名称: Tretinoin;All-trans Retinoic Acid
CAS号: 产品包装: 10mg/252RMB;200mg/674RMB 产品价格: 252RMB
有效期: 品牌: 产地:
保存条件: 纯度规格: 产品类别: 激动剂抑制剂

产品描述:

公告提醒:爱必信所有产品和服务仅用于科学研究不用于临床应用及其他用途提供产品和服务也不为任何个人提供产品和服务)!

 

抑制剂描述:

产品名称:Tretinoin

产品别名:维生素A酸

英文别名:All-trans Retinoic Acid

靶点:RAR ,RXR

CAS:302-79-4

 

纯度:0.99

外观:Powder

保存方法:store at -20℃ for one year(Powder); in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months.

描述:

An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).

 

溶解性:DMSO 60 mg/mL
Ethanol 6 mg/mL

体外研究:

Tretinoin prevents the cytotoxicity of H2O2 in cultured human mesangial cells by increasing both the catalase activity and the reduced glutathione content, which are dose- and time-dependent changes. Tretinoin-incubated mesangial cells leads to increased levels of catalase mRNA and gamma-glutamyl-cysteine synthetase (catalytic subunit) mRNA, the latter being the rate-limiting step in de novo reduced glutathione synthesis. Tretinoin upregulates matrix metalloproteinase-13 and matrix metalloproteinase-8 in human keloid-derived fibroblasts.

 

体内研究:Tretinoin-treated old male Fischer 344 rats have 30% lower protein content in the renal cortex than control old rats, this effect may depend on the inhibition of the expression of tumor necrosis factor-beta1, a matrigenic cytokine, and osteopontin, a protein with cell adhesive and chemotactic properties. Tretinoin has the ability to prevent the major steroid-induced biomechanical changes in hairless mouse dermal connective tissue that contribute to atrophy. Tretinoin combined with imiquimod leads to faded tattoos and moderate clearance of pigment on histopathology in the guinea pig. Tretinoin increases fibroplastic proliferation in the Skin incisions were made in 45 CD-1 mice, but the production of collagen was diminished.

 

产品信息订购:

  产品货号
  产品名称
  规格
价格
大包装及货期
  abs812855
  Tretinoin
  10mg
  240
  立即咨询

产品更多信息请进入爱必信网站咨询

关键字:Tretinoin;All-trans Retinoic Acid

供应商联系方式:

  • 联系人: 郭小姐
  • 公司名称: 爱必信(上海) 生物科技有限公司
  • 电话:021-38015121
  • 手机: 15502157206
  • 传真 :
  • 邮箱 :info@absin.cn
  • 地址 : 上海市浦东新区新浩路58号18号楼

公司简介:

爱必信(上海)生物科技有限公司成立于2010年,位于上海市申江科创园。是一家自主研发和生产生物试剂的公司。 Absin?是爱必信(上海)生物科技有限公司的试剂品牌,目前已近60万种生化试剂,10万种抗体,其基础生化试剂在基础科学领域得到广泛应用的同时,特色产品线常规生化试剂,血清,小分子激动剂及抑制剂在业界也备受好评。 Absin秉承踏实,务实,求精和不断创新的精神为中国科学家提供最好的产品,努力打造属于中国自己的生物试剂品牌,为广大科学家提供更全面更丰富更优质的产品。 爱科研,必信它(Absin)!Absin努力成为你身边的科研百宝箱!

Tretinoin;All-trans Retinoic Acid 生产厂家及价格列表:

产品名称 价格 公司名称 发布日期


供应商其他产品:

Human IL-23 ELISA KitMouse TNF alpha ELISA KitGoat anti-Rabbit IgG-AlexaFluor 488
Human IL-6 ELISA KitHuman EGF ELISA KitHuman PD-L1/B7-H1 ELISA KIT
盐酸可乐定Anti- HA 抗体Human IL-1 beta ELISA kit
Human IL-1 beta ELISA kitRat IL-6 ELISA KitDL 15000 DNA Marker
His(C-terminal Specific) 小鼠单克隆抗体甲基泼尼松龙;甲泼尼龙Human PD-1 ELISA KIT
Human MMP-9 ELISA KitMouse IL-1 beta ELISA KITMouse VEGF ELISA Kit
Apatinib; YN968D1Epacadostat (INCB024360)FH 535; FH-535
PP 2; AG1879; AG 1879,AGL 1879LBH-589(Panobinostat)LEE 011; LEE-011,Ribociclib,LEE011
PSI-7977,GS-7977,PSI 7977,GS 7977,sofosbuvirThiazovivinNVP-BKM120(Buparlisib)
Ertapenem;厄他培南Rivaroxaban; BAY 59-7939INT-747(Obeticholic acid)
PD0332991(free base)TirofibanNSC 123127;Adriamycin; Hydroxydaunorubicin hydrochloride;
Bay 43-9006,Bay43-9006JQ-1,JQ 1,JQ1,+JQ 1,+JQ-1,+JQ1BML-284; 2-Amino-4-[3,4-(methylenedioxy)benzylamino]-6-(3-methoxyphenyl)pyrimidine
Vorinostat (SAHA)Apatinib Mesylate;YN968D1Captopril;A333;甲巯丙脯酸
胆固醇GAPDH 小鼠单克隆抗体β-tubulin 小鼠单克隆抗体
human IL2 重组蛋白; T-cell growth factor;TCGFCollagen I Antibodyanti-Mouse IgG-FITC;IgG-FITC抗体
Mouse IL-12 p70 ELISA KITMC1568;MC 1568;MC-1568IWP-2;ABC 294640;ABC-294640
ABT199;GDC0199;ABT 199;GDC 0199;GDC-0199;VenetoclaxTretinoin;All-trans Retinoic AcidRW22164;RWJ22164
二甲基亚砜(DMSO)(AR级)Rabbit anti-TLR4 Polyclonal Antibodybeta I Tubulin Antibody
Tubulin alpha AntibodyGoat anti-Rabbit IgG-FITCGoat anti-Rabbit IgG-Cy3
二硫苏糖醇(DTT);1,4二巯基苏糖醇Human TNF-α ELISA KitHuman VEGF ELISA Kit
Mouse IL-2 ELISA KITMouse IL-4 ELISA KITHuman IL-2 ELISA Kit
Human IL-10 ELISA KitDL 5000 DNA MarkerXAV939;NVP-XAV 939
CapecitabineBenzatropine mesylate; Benzotropine mesylate;Benztropine methanesulfonate;甲磺酸苯扎托品替米沙坦
SCH 13521;FlutamideProstaglandin E1;PGE1Cordycepin;3'-Deoxyadenosine
Imatinib;STI571组织/细胞裂解液 (多因子检测)ERBB2 Antibody
BAP31 Antibody洛匹那韦(Lopinavir)地瑞那韦
盐酸阿比朵尔(Arbidol hydrochloride) 沙奎那韦(Saquinavir)2019-nCoV S蛋白
2019-nCoV S1蛋白Human inflammatory factor multi-assay kit抗人CD16单克隆抗体
抗人CD20单克隆抗体抗人 CD28 单克隆抗体抗人 CD3 单克隆抗体
抗人PD-1单克隆抗体GST融合蛋白纯化磁珠His-tag蛋白纯化磁珠
Ni Sepharose 6 Fast Flow His标签蛋白纯化填料(镍柱纯化填料)Xeno-Free人间充质干细胞培养基Xeno-Free人间充质干细胞培养基(无酚红)
人多能干细胞分化培养基人多能干细胞完全培养基人多能干细胞条件培养基
人多能干细胞消化液人脂肪干细胞无血清培养基(无酚红)人脐带间充质干细胞无血清培养基(无酚红)