度洛西汀

Product name

Duloxetine Hydrochloride

Other name

(R)-Doluxitine;(r)-duloxetine; (R)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-aMine hydrochloride; (r)-n-methyl-gama-(1-naphthalenyloxy)-2-thiophenepropanamine; Duloxetine hydrochloride impurity A; Duloxetine hydrochloride impurity A –G; R-DULOXETINE HCL;  R-DULOXETINE Oxalate

CAS NO.

116539-60-7

OTHER CAS NO.

136434-34-9

M.F.

C₁₈H₂₀ClNOS

M.W

333.87600

EINECS

1312995-182-4

Structure

Chemical Properties

PSA

49.50000

Density

1.158

boiling point

466.2ºC at 760 mmHg

flash point

235.7ºC

Package

25kg drum

Certification

GMP factory

Item

Specification

Character

A white or almost white powder

Solubility

Sparingly Soluble in water ;freely soluble in methanol; don’t soluble in hexane

Loss on drying

NMT0.50%

Heavy metals

NMT 10ppm

Sulfated ash

Nmt0.10%

Related substance

Impurity F NMT 0.40%

Any other impurity NMT 0.10%

Total impurities NMT0.50%

Assay

98.5%-102.0%