Drospirenone manufacturers and suppliers in india

Drospirenone

Properties

Melting point:: 196-200°C

alpha: -180 º (c=0.5, chloroform)

Boiling point:: 552.2±50.0 °C(Predicted)

Density: 1.26±0.1 g/cm3(Predicted)

storage temp.: 2-8°C

solubility: DMSO: ≥15

form: powder

color: white to tan

optical activity: [α]/D -180 to -195°, c = 1 in methanol

InChIKey: METQSPRSQINEEU-URUUTGNFNA-N

SMILES: C[C@]12CC[C@]3([H])[C@]4(CCC(=O)C=C4[C@@H]4C[C@@H]4[C@@]3([H])[C@]1([H])[C@@H]1C[C@@H]1[C@]12CCC(=O)O1)C |&1:1,4,6,13,15,16,18,20,22,23,r|

Safety Information

Symbol(GHS): GHS08

Signal word: Danger

Hazard statements: H360

Precautionary statements: P201-P202-P280-P308+P313-P405-P501

Hazard Codes: T

Risk Statements: 60

Safety Statements: 36/37

WGK Germany: 3

RTECS: WH1299000

HS Code: 2937230000

Hazardous Substances Data: 67392-87-4(Hazardous Substances Data)

Use

Drospirenone is the only progesterone that has the characteristics similar to the natural progesterone currently, its structure is more like that of the natural progesterone compare with the structure of the progesterone contained in the traditional oral contraceptives. Except the effect of anti-androgen, drospirenone has the role of anti-mineralocorticoid which can prevent water and sodium retain in the body. Not only it has the a great effectivenes of contraception, there are also many good impacts on women's health like reducing the acne, making the skin more smooth and controling the weight efficaciously.