Ketoconazole
Ketoconazole
- CAS:
- 65277-42-1
- MF:
- C26H28Cl2N4O4
- MW:
- 531.43
Suppliers by country/region
- India(202)
- CHINA(364)
- United States(98)
- United Kingdom(26)
- Canada(13)
- Switzerland(4)
- South Korea(3)
- Germany(16)
- Europe(2)
- Slovakia(1)
- France(5)
- Ukraine(1)
- Japan(3)
- Philippines(1)
- Spain(10)
- Mexico(3)
- Slovenia(1)
- Brazil(6)
- Austria(3)
- Belgium(6)
- Australia(1)
- Greece(1)
- Nigeria(1)
- The Netherlands(1)
- Italy(2)
- Indonesia(1)
- Poland(2)
- Argentina(1)
- Singapore(1)
- Czech Republic(1)
- Malaysia(1)
- Nepal(1)
- Egypt(1)
- Jordan(1)
- United Arab Emirates(1)
Company Type
Properties
- Melting point:
- 148-152 °C
- Boiling point:
- 753.4±60.0 °C(Predicted)
- Density
- 1.4046 (rough estimate)
- refractive index
- -10.5 ° (C=0.4, CHCl3)
- Flash point:
- 9℃
- storage temp.
- 2-8°C
- solubility
- methanol: soluble50mg/mL
- pka
- pKa 3.25/6.22(H2O,t =25,I=0.025) (Uncertain)
- form
- Off-white solid
- color
- white to light yellow
- optical activity
- [α]20/D -1 to 1°, c = 4 in methanol
- Water Solubility
- Soluble in DMSO, ethanol, chloroform, water, and methanol.
- Merck
- 14,5302
- BCS Class
- 2
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
- InChIKey
- XMAYWYJOQHXEEK-OZXSUGGESA-N
- LogP
- 4.350
- CAS DataBase Reference
- 65277-42-1(CAS DataBase Reference)
Safety Information
- Symbol(GHS)
GHS06,GHS08,GHS09
- Signal word
- Danger
- Hazard statements
- H301-H360F-H373-H410
- Precautionary statements
- P201-P202-P260-P264-P273-P301+P310
- Hazard Codes
- T,N,F
- Risk Statements
- 25-36/37/38-23/24/25-50/53-48/22-60-39/23/24/25-11
- Safety Statements
- 36-45-36/37/39-26-61-60-53-36/37-16-7
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- TK7912300
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29349990
- Hazardous Substances Data
- 65277-42-1(Hazardous Substances Data)
- Toxicity
- LD50 in mice, rats, guinea pigs, dogs (mg/kg): 44, 86, 28, 49 i.v.; 702, 227, 202, 780 orally (Heel)
- Limited Quantities
- 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
- Excepted Quantities
- Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
Use
Ketoconazole is used to treat candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis. Ketoconazole is an antifungal agent. It inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor.
202 India supplier list of "Ketoconazole"
- Product Name:Ketoconazole
- Company Type: Reagent
- Country/Region: INDONESIA
- Product Name:Ketoconazole
- Products Intro:Purity: 99 | Package: 25公斤/桶
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Ketoconazole
- Company Type: Reagent
- Country/Region: BRAZIL
- Product Name:Ketoconazole
- Products Intro:Purity: 99 | Package: 1kg;25kg;1000kg
- Company Type: Service provider
- Country/Region: CHINA
- Product Name:Ketoconazole
- Company Type: Reagent
- Country/Region: MEXICO
- Product Name:Ketoconazole
- Products Intro:Purity: 99%
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Ketoconazole
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Ketoconazole
- Company Type: Reagent
- Country/Region: UNITED KINGDOM
- Product Name:ketoconazole
- Products Intro:Purity: 99
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Ketoconazole
- Company Type: Reagent
- Country/Region: GERMANY