Chemical Safety Data Sheet MSDS / SDS

1-Methylimidazole

Revision Date:2024-05-18Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: 1-Methylimidazole
  • CBnumber: CB1316726
  • CAS: 616-47-7
  • EINECS Number: 210-484-7
  • Synonyms: 1-Methylimidazole,N-methylimidazole

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 400-158-6606

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordDanger
Precautionary statements
P405 Store locked up.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
Hazard statements
H314 Causes severe skin burns and eye damage
H312 Harmful in contact with skin
H311 Toxic in contact with skin
H302 Harmful if swallowed
H227 Combustible liquid

SECTION 3: Composition/information on ingredients

Substance

  • Product name: 1-Methylimidazole
  • Synonyms: 1-Methylimidazole,N-methylimidazole
  • CAS: 616-47-7
  • EC number: 210-484-7
  • MF: C4H6N2
  • MW: 82.1

SECTION 4: First aid measures

Description of first aid measures

General advice
First aider needs to protect himself. Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Call in physician.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Call a physician immediately.
In case of eye contact
After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: make victim drink water (two glasses at most), avoid vomiting (risk of perforation). Call a physician immediately. Do not attempt to neutralise.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5: Firefighting measures

Extinguishing media

Suitable extinguishing media
Water Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.

Special hazards arising from the substance or mixture

Carbon oxides Nitrogen oxides (NOx)

Vapors may form explosive mixture with air.

Combustible.

Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating.

Development of hazardous combustion gases or vapours possible in the event of fire.

Advice for firefighters

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

Further information

Remove container from danger zone and cool with water. Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.

NFPA 704

3
2
1
HEALTH 3 Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid)
FIRE 2 Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur and multiple finely divided suspended solids that do not require heating before ignition can occur. Flash point between 37.8 and 93.3 °C (100 and 200 °F). (e.g. diesel fuel, sulfur)
REACT 1 Normally stable, but can become unstable at elevated temperatures and pressures (e.g. propene)
SPEC. HAZ.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.

Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.

Environmental precautions

Do not let product enter drains.

Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.

Chemizorb?). Dispose of properly. Clean up affected area.

Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

Precautions for safe handling

Advice on protection against fire and explosion

Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.

Hygiene measures

Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.

For precautions see section 2.2.

Conditions for safe storage, including any incompatibilities

Storage conditions

Handle under nitrogen, protect from moisture. Store under nitrogen.

Tightly closed. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons.

Hygroscopic.

Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

control parameter

Hazard composition and occupational exposure limits
Does not contain substances with occupational exposure limits.

Exposure controls

Personal protective equipment
Eye/face protection

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Tightly fitting safety goggles

Skin protection

This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Full contact

Material: butyl-rubber

Minimum layer thickness: 0,7 mm Break through time: 480 min Material tested:Butoject? (KCL 898)

This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Splash contact Material: Latex gloves

Minimum layer thickness: 0,6 mm Break through time: 30 min

Material tested:Lapren? (KCL 706 / Aldrich Z677558, Size M)

Body Protection

protective clothing

Respiratory protection

Recommended Filter type: Filter A (acc. to DIN 3181) for vapours of organic compounds

The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.

These measures have to be properly documented.

Control of environmental exposure

Do not let product enter drains.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • Appearancecolorless liquid, clear
  • OdourNo data available
  • Odour ThresholdNo data available d) pH 9,5 - 11,5 at 100 g/l at 20 °C Melting point/freezing point Initial boiling point and boiling range Melting point/range: -6 °C 198 °C Flash point 92 °C - closed cup Evaporation rate No data available Flammability (solid, gas) Upper/lower flammability or explosive limits No data available Upper explosion limit: 15,7 %(V) Lower explosion limit: 2,7 %(V) Vapour pressure 0,5 hPa at 20 °C Vapour density No data available Relative density 1,03 g/mL at 25 °C Water solubility soluble Partition coefficient: n-octanol/water Autoignition temperature Decomposition temperature log Pow: -0,19 at 25 °C 488 °C at 1.013 - 1.019 hPa No data available Viscosity Viscosity, kinematic: No data available Viscosity, dynamic: 1,89 mPa.s at 20 °C Explosive properties No data available Oxidizing properties No data available
  • Melting point/freezing pointMelting point/range: -6 °C
  • Initial boiling point and boiling range198 °C
  • Flash point92 °C - closed cup
  • Evaporation rate198 °F
  • Flammability (solid, gas)No data available
  • Upper/lower flammability or explosive limits Upper explosion limit: 15,7 %(V) Lower explosion limit: 2,7 %(V)
  • Vapour pressure 0,5 hPa at 20 °C
  • Vapour density 0.4 mm Hg ( 20 °C)
  • Relative density1,03 g/mL at 25 °C
  • Water solubilitysoluble
  • Partition coefficient: n-octanol/waterlog Pow: -0,19 at 25 °C
  • Autoignition temperature488 °C at 1.013 - 1.019 hPa
  • Decomposition temperature No data available
  • ViscosityViscosity, kinematic: No data available Viscosity, dynamic: 1,89 mPa.s at 20 °C
  • Explosive propertiesNo data available
  • Oxidizing propertiesNo data available

Other safety information

No data available

SECTION 10: Stability and reactivity

Reactivity

Forms explosive mixtures with air on intense heating.

A range from approx. 15 Kelvin below the flash point is to be rated as critical.

Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

Possibility of hazardous reactions

Violent reactions possible with:

Acid anhydrides Acid chlorides

Strong oxidizing agents acids


Conditions to avoid

Exposure to moisture. Strong heating.

Incompatible materials

rubber, various plastics

Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

Information on toxicological effects

Acute toxicity
LD50 Oral - Rat - male and female - 1.144 mg/kg (OECD Test Guideline 401)
LD50 Dermal - Rabbit - male and female - 400 - 600 mg/kg (OECD Test Guideline 402)
Skin corrosion/irritation
Skin - Rabbit Result: Corrosive
(OECD Test Guideline 404)
Serious eye damage/eye irritation
Eyes - Rabbit Result: Corrosive
(OECD Test Guideline 405)
Respiratory or skin sensitization
No data available
Germ cell mutagenicity
Result: negative
Carcinogenicity
IARC: No ingredient of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
Toxicity
LD50 orally in Rabbit: 1144 mg/kg LD50 dermal Rabbit > 400 - < 640 mg/kg

SECTION 12: Ecological information

Toxicity

Toxicity to fish
static test LC50 - Leuciscus idus (Golden orfe) - > 100 - 215 mg/l - 96 h

Toxicity to daphnia and other aquatic invertebrates

EC50 - Daphnia magna (Water flea) - 267,94 mg/l - 48 h

Toxicity to algae
static test EC50 - Desmodesmus subspicatus (green algae) - 180,7 mg/l - 72 h

(OECD Test Guideline 201)

Persistence and degradability

Biodegradability aerobic - Exposure time 28 d

Result: 0 - 10 % - Not readily biodegradable. (OECD Test Guideline 301F)

Bioaccumulative potential

No data available

Mobility in soil

No data available

Results of PBT and vPvB assessment

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

Other adverse effects

May be harmful to aquatic organisms due to the shift of the pH.

SECTION 13: Disposal considerations

Waste treatment methods

Product

See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.

SECTION 14: Transport information

UN number

ADR/RID: 2922 IMDG: 2922 IATA: 2922

UN proper shipping name

ADR/RID: CORROSIVE LIQUID, TOXIC, N.O.S. (1-Methylimidazole) IMDG: CORROSIVE LIQUID, TOXIC, N.O.S. (1-Methylimidazole)

IATA: Corrosive liquid, toxic, n.o.s. (1-Methylimidazole)

Transport hazard class(es)

ADR/RID: 8 (6.1) IMDG: 8 (6.1) IATA: 8 (6.1)

Packaging group

ADR/RID: II IMDG: II IATA: II

Environmental hazards

ADR/RID: no IMDG Marine pollutant: no IATA: no

Special precautions for user

No data available

SECTION 15: Regulatory information

Safety, health and environmental regulations/legislation specific for the substance or mixture

Regulations on the Safety Management of Hazardous Chemicals
China Catalog of Hazardous chemicals 2015:Not Listed. website: https://www.mem.gov.cn/
Measures for Environmental Management of New Chemical Substances
Vietnam National Chemical Inventory:Listed. website: https://chemicaldata.gov.vn/
United States Toxic Substances Control Act (TSCA) Inventory:Listed. website: https://www.epa.gov/
Philippines Inventory of Chemicals and Chemical Substances (PICCS):Listed. website: https://emb.gov.ph/
New Zealand Inventory of Chemicals (NZIoC):Listed. website: https://www.epa.govt.nz/
Korea Existing Chemicals List (KECL):Listed. website: http://ncis.nier.go.kr
European Inventory of Existing Commercial Chemical Substances (EINECS):Listed. website: https://echa.europa.eu/
EC Inventory:Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC):Listed. website: https://www.mee.gov.cn/

SECTION 16: Other information

Abbreviations and acronyms

  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • CAS: Chemical Abstracts Service
  • EC50: Effective Concentration 50%
  • IATA: International Air Transportation Association
  • IMDG: International Maritime Dangerous Goods
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • STEL: Short term exposure limit
  • TWA: Time Weighted Average

References

【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple

【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp

【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/

【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en

【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg

【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp

【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm

【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/

【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home

【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/

Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

Recommended Products
1,1'-Carbonyldiimidazole SDS 1,1'-Thiocarbonyldiimidazole SDS 2-Ethyl-4-methylimidazole SDS 4'-(IMIDAZOL-1-YL)ACETOPHENONE SDS 1-Butyl-3-methylimidazolium chloride SDS N-(Trimethylsilyl)imidazole SDS 2-Methylimidazole SDS Imidazo[1,2-a]pyridine SDS 1-Vinylimidazole SDS 4-Methyl-5-imidazolemethanol hydrochloride SDS