2-Mercaptoethanol
Product identifier
- Product name: 2-Mercaptoethanol
- CBnumber: CB8215961
- CAS: 60-24-2
- EINECS Number: 200-464-6
- Synonyms: 2-mercaptoethanol,mercaptoethanol
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
Substance
- Product name: 2-Mercaptoethanol
- Synonyms: 2-mercaptoethanol,mercaptoethanol
- CAS: 60-24-2
- EC number: 200-464-6
- MF: C2H6OS
- MW: 78.13
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides, Sulfur oxides Combustible.
Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating.
Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.
Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Further information
Remove container from danger zone and cool with water. Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
| HEALTH | 3 | Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid) | |
| FIRE | 2 | Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur and multiple finely divided suspended solids that do not require heating before ignition can occur. Flash point between 37.8 and 93.3 °C (100 and 200 °F). (e.g. diesel fuel, sulfur) | |
| REACT | 1 | Normally stable, but can become unstable at elevated temperatures and pressures (e.g. propene) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb?). Dispose of properly. Clean up affected area.
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols. Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Tightly closed. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons.
Recommended storage temperature 2 - 8 °C
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Appropriate engineering controlsImmediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Tightly fitting safety goggles
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Full contact
Material: butyl-rubber
Minimum layer thickness: 0,7 mm Break through time: 480 min Material tested:Butoject? (KCL 898)
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Splash contact Material: Nitrile rubber
Minimum layer thickness: 0,4 mm Break through time: 120 min
Material tested:Camatril? (KCL 730 / Aldrich Z677442, Size M)
protective clothing
required when vapours/aerosols are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Do not let product enter drains.
Information on basic physicochemical properties
- Appearancecolorless liquid
- Odourcharacteristic
- Odour Threshold5,7 ppm d) pH 4,5 - 6 at 500 g/l at 20 °C Melting point/freezing point Initial boiling point and boiling range Melting point:< -50 °C 157 °C - lit. Flash point 74 °C - closed cup Evaporation rate No data available Flammability (solid, gas) Upper/lower flammability or explosive limits No data available Upper explosion limit: 18 %(V) Lower explosion limit: 2,3 %(V) Vapour pressure 0,76 hPa at 20 °C Vapour density 2,70 - (Air = 1.0) Relative density 1,114 g/cm3 at 25 °C Water solubility soluble Partition coefficient: n-octanol/water Autoignition temperature Decomposition temperature log Pow: -0,056 at 25 °C - Bioaccumulation is not expected. No data available No data available Viscosity No data available Explosive properties No data available Oxidizing properties No data available
- Melting point/freezing pointMelting point:< -50 °C
- Initial boiling point and boiling range 157 °C - lit.
- Flash point74 °C - closed cup
- Evaporation rate165 °F
- Flammability (solid, gas)No data available
- Upper/lower flammability or explosive limits Upper explosion limit: 18 %(V) Lower explosion limit: 2,3 %(V)
- Vapour pressure 0,76 hPa at 20 °C
- Vapour density 2,70 - (Air = 1.0)
- Relative density1,114 g/cm3 at 25 °C
- Water solubilitysoluble
- Partition coefficient: n-octanol/waterlog Pow: -0,056 at 25 °C - Bioaccumulation is not expected.
- Autoignition temperatureNo data available
- Decomposition temperatureNo data available
- ViscosityNo data available
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
- λmaxλ: 260 nm Amax: 1.5
λ: 280 nm Amax: 0.3
Other safety information
Relative vapor density
2,70 - (Air = 1.0)
Reactivity
Forms explosive mixtures with air on intense heating.
A range from approx. 15 Kelvin below the flash point is to be rated as critical.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions
No data available
Conditions to avoid
Strong heating.
Incompatible materials
Metals, Oxidizing agents
Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides, Sulfur oxides
Other decomposition products - No data available In the event of fire: see section 5
Information on toxicological effects
Acute toxicityRemarks: (RTECS)
LC50 Inhalation - Rat - male - 4 h - 2,05 mg/l Remarks: (ECHA)
LD50 Dermal - Rabbit - male and female - 112 - 224 mg/kg Remarks: (ECHA)
(OECD Test Guideline 404)
Result: Severe irritations (Draize Test)
Remarks: (External MSDS) Risk of corneal clouding.
Mouse - male and female - Bone marrow Result: negative
Acute oral toxicity - Irritations of mucous membranes in the mouth, pharynx, oesophagus and gastrointestinal tract.
Acute inhalation toxicity - Possible damages:, mucosal irritations, Cough, Shortness of breath
Oral - Liver, Heart
RTECS: KL5600000
burning sensation, Cough, wheezing, laryngitis, Shortness of breath, Headache, Nausea, Vomiting, Weakness, Unconsciousness, Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi, pneumonitis, pulmonary edema
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Systemic effects:
CNS disorders, Nausea, Vomiting, Convulsions, narcosis
The following applies to mercaptans in general: offensive odour. Other dangerous properties can not be excluded.
This substance should be handled with particular care.
Toxicity
static test EC50 - Daphnia magna (Water flea) - 0,4 mg/l - 48 h (OECD Test Guideline 202)
(OECD Test Guideline 201)
Persistence and degradability
Biodegradability Result: > 70 % - rapidly biodegradable Remarks: (ECHA)
Biochemical Oxygen 105 mg/g
Demand (BOD) Remarks: (IUCLID)
Chemical Oxygen Demand (COD)
1,894 mg/g Remarks: (IUCLID)
Bioaccumulative potential
Does not accumulate in organisms.
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
Additional ecological information
No data available
Waste treatment methods
Product
See www.retrologistik.com for processes regarding the return of chemicals and
containers, or contact us there if you have further questions.
UN number
UN proper shipping name
Transport hazard class(es)
ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1
Packaging group
ADR/RID: II IMDG: II IATA: II
Environmental hazards
ADR/RID: yes IMDG Marine pollutant: yes IATA: no
Special precautions for user
No data available
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- CAS: Chemical Abstracts Service
- EC50: Effective Concentration 50%
- IATA: International Air Transportation Association
- IMDG: International Maritime Dangerous Goods
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- STEL: Short term exposure limit
- TWA: Time Weighted Average
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.