ChemicalBook
Chemical Safety Data Sheet MSDS / SDS

3-PHOSPHOGLYCERIC PHOSPHOKINASE

Revision Date:2026-03-21Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: 3-PHOSPHOGLYCERIC PHOSPHOKINASE
  • CBnumber: CB5273944
  • CAS: 9001-83-6
  • EINECS Number: 232-636-1
  • Synonyms: EC 2.7.2.3;3-Phosphoglycerate (3PG)

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordWarning
Precautionary statements
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.
Hazard statements
H319 Causes serious eye irritation

SECTION 3: Composition/information on ingredients

Substance

  • Product name: 3-PHOSPHOGLYCERIC PHOSPHOKINASE
  • Synonyms: EC 2.7.2.3;3-Phosphoglycerate (3PG)
  • CAS: 9001-83-6
  • EC number: 232-636-1
  • MF: NULL

SECTION 4: First aid measures

4.1 Description of first-aid measures

General advice
Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Consult doctor if feeling unwell.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.
In case of eye contact
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.

4.2 Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11

4.3 Indication of any immediate medical attention and special treatment needed

No data available

4.4 Notes to physician

No data available

SECTION 5: Firefighting measures

5.1 Extinguishing media

Suitable extinguishing media
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.

5.2 Special hazards arising from the substance or mixture

Nitrogen oxides (NOx)
Sulfur oxides
Oxides of phosphorus
Sodium oxides
Not combustible.
Ambient fire may liberate hazardous vapours.

5.3 Advice for firefighters

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.

6.2 Environmental precautions

Do not let product enter drains.

6.3 Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb® ).
Dispose of properly. Clean up affected area.

6.4 Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling

For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Storage conditions
Tightly closed.
Storage stabilityRecommended storage temperature
2 - 8 °C
Storage class
Storage class (TRGS 510): 12: Non Combustible Liquids

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Ingredients with workplace control parameters
Contains no substances with occupational exposure limit values.

8.2 Exposure controls

Appropriate engineering controls
Change contaminated clothing. Wash hands after working with substance.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
required
Body Protection
protective clothing
Respiratory protection
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Control of environmental exposure
Do not let product enter drains.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • a) Physical statesuspension
  • b) ColorColorless to light yellow
  • c) OdorNo data available
  • d) Melting point/freezing pointNo data available
  • e) Initial boiling point and boiling rangeNo data available
  • f) Flammability (solid, gas)No data available
  • g) Upper/lower flammability or explosive limitsNo data available
  • h) Flash pointNo data available
  • i) Autoignition temperatureNot applicable
  • j) Decomposition temperatureNo data available
  • k) pHNo data available
  • l) ViscosityViscosity, kinematic: No data available
    Viscosity, dynamic: No data available
  • m) Water solubilityNo data available
  • n) Partition coefficient n-octanol/waterNo data available
  • o) Vapor pressureNo data available
  • p) DensityNo data available
  • Relative densityNo data available
  • q) Relative vapor densityNo data available
  • r) Particle characteristicsNo data available
  • s) Explosive propertiesNot classified as explosive.
  • t) Oxidizing propertiesnone

9.2 Other safety information

No data available

SECTION 10: Stability and reactivity

10.1 Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

10.2 Possibility of hazardous reactions

No data available

10.3 Conditions to avoid

no information available

10.4 Incompatible materials

Strong oxidizing agents

10.5 Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Mixture Acute toxicity
Acute toxicity estimate Oral - > 5,000 mg/kg (Calculation method)
Symptoms: Possible symptoms:, mucosal irritations
Dermal: No data available
Skin corrosion/irritation
Classified based on available data. For more details, see section 2
Serious eye damage/eye irritation
Remarks: Mixture causes serious eye irritation.
Respiratory or skin sensitization
Mixture may produce an allergic reaction.
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2

11.2 Additional Information

To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
Components ammonium sulphate
Acute toxicity
LD50 Oral - Rat - male and female - 4,250 mg/kg (OECD Test Guideline 401)
Inhalation: No data available
LD50 Dermal - Rat - male and female - > 2,000 mg/kg (OECD Test Guideline 434)
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation - 20 h
Remarks: (ECHA)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: No eye irritation
Remarks: (ECHA)
Respiratory or skin sensitization
Maximization Test - Guinea pig
Result: negative (US-EPA)
Germ cell mutagenicity
Test Type: Ames test
Test system: S. typhimurium
Result: negative
Test Type: Mutagenicity (mammal cell test): chromosome aberration.
Test system: Human lymphocytes
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster lung cells
Result: negative
Species: Mouse - male - Bone marrow
Remarks: (ECHA)
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure Aspiration hazard
Classified based on available data. For more details, see section 2
tetrasodium diphosphate
Acute toxicity
LD50 Oral - Rat - female - > 300 - < 2,000 mg/kg (OECD Test Guideline 420)
LC50 Inhalation - Rat - male and female - 4 h - > 0.58 mg/l - dust/mist (OECD Test Guideline 403)
Remarks: (highest concentration to be prepared)
The value is given in analogy to the following substances: Disodium pyrophosphate
LD50 Dermal - Rabbit - male and female - > 2,000 mg/kg (US-EPA)
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation - 4 h (OECD Test Guideline 404)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Irreversible effects on the eye - 4 h (OECD Test Guideline 405)
Respiratory or skin sensitization
Local lymph node assay (LLNA) - Mouse
Result: negative (OECD Test Guideline 429)
Remarks: The value is given in analogy to the following substances: Disodium pyrophosphate
Germ cell mutagenicity
Test Type: gene mutation test
Test system: Mouse lymphoma test
Result: negative
Test Type: Micronucleus test
Test system: lymphocyte
Result: negative
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure Aspiration hazard
Classified based on available data. For more details, see section 2
Kinase (phosphorylating), phosphoglycerate
Acute toxicity
Oral: No data available
Inhalation: No data available
Dermal: No data available
Skin corrosion/irritation
Remarks: No data available
Serious eye damage/eye irritation
Remarks: No data available
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2

SECTION 12: Ecological information

12.1 Toxicity

Mixture
No data available

12.2 Persistence and degradability

No data available

12.3 Bioaccumulative potential

No data available

12.4 Mobility in soil

No data available

12.5 Results of PBT and vPvB assessment

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

12.6 Endocrine disrupting properties

No data available

12.7 Other adverse effects

No data available
Components ammonium sulphate
Toxicity to fish LC50 - Oncorhynchus mykiss (rainbow trout) - 53 mg/l - 96 h
Remarks: (ECHA)
Toxicity to daphnia static test EC50 - Ceriodaphnia (water flea) - 121.7 mg/l - 48 and other aquatic h invertebrates (US-EPA)
Toxicity to algae static test ErC50 - Chlorella vulgaris (Fresh water algae) - 2,700 mg/l - 18 Days
Remarks: (ECHA)
Toxicity to bacteria static test EC50 - activated sludge - 1,618 mg/l - 30 min (OECD Test Guideline 209)
Toxicity to flow-through test EC10 - Lepomis macrochirus - 5.29 mg/l - 30 fish(Chronic toxicity) d
Remarks: (ECHA)
Toxicity to daphnia semi-static test EC10 - Daphnia - 3.12 mg/l - 70 d and other aquatic (US-EPA) invertebrates(Chronic toxicity)
tetrasodium diphosphate
Toxicity to fish semi-static test LC50 - Oncorhynchus mykiss (rainbow trout) - > 100 mg/l - 96 h (OECD Test Guideline 203)
Toxicity to daphnia static test EC50 - Daphnia magna (Water flea) - > 100 mg/l - and other aquatic 48 h invertebrates (US-EPA)
Toxicity to algae static test ErC50 - Desmodesmus subspicatus (green algae) - > 100 mg/l - 72 h (OECD Test Guideline 201) static test NOEC - Desmodesmus subspicatus (green algae) - > 100 mg/l - 72 h (OECD Test Guideline 201)
Toxicity to bacteria static test EC50 - activated sludge - > 1,000 mg/l - 3 h (OECD Test Guideline 209)
Remarks: The value is given in analogy to the following substances: dipotassium hydrogen phosphate
Kinase (phosphorylating), phosphoglycerate
No data available

SECTION 13: Disposal considerations

13.1 Waste treatment methods

Product
Offer surplus and non-recyclable solutions to a licensed disposal company.

SECTION 14: Transport information

14.1 UN number

ADR/RID: -
IMDG: -
IATA-DGR: -

14.2 UN proper shipping name

ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA-DGR: Not dangerous goods

14.3 Transport hazard class(es)

ADR/RID: -
IMDG: -
IATA-DGR: -

14.4 Packaging group

ADR/RID: -
IMDG: -
IATA-DGR: -

14.5 Environmental hazards

ADR/RID: no
IMDG Marine pollutant: no
IATA-DGR: no

14.6 Special precautions for user

14.7 Incompatible materials

Strong oxidizing agents
Further information: Not classified as dangerous in the meaning of transport regulations.

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture

National regulatory information
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.

SECTION 16: Other information

Abbreviations and acronyms

CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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