Halothane

Skin irritation, Category 2

Serious eye damage, Category 1

Specific target organ toxicity – single exposure, Category 3

Reproductive toxicity, Category 1B

H315 Causes skin irritation

H318 Causes serious eye damage

H335 May cause respiratory irritation

H341 Suspected of causing genetic defects

H360 May damage fertility or the unborn child

P201 Obtain special instructions before use.

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313 IF exposed or concerned: Get medical advice/attention.

P405 Store locked up.

P264 Wash ... thoroughly after handling.

P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

P271 Use only outdoors or in a well-ventilated area.

P203 Obtain, read and follow all safety instructions before use.

P302+P352 IF ON SKIN: Wash with plenty of water/...

P321 Specific treatment (see ... on this label).

P332+P317 If skin irritation occurs: Get medical help.

P362+P364 Take off contaminated clothing and wash it before reuse.

P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

P317 Get medical help.

P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P319 Get medical help if you feel unwell.

P318 IF exposed or concerned, get medical advice.

P403+P233 Store in a well-ventilated place. Keep container tightly closed.

P405 Store locked up.

P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

no data available

Fresh air, rest. Refer for medical attention.

Remove contaminated clothes. Rinse skin with plenty of water or shower.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Do NOT induce vomiting. Refer for medical attention .

Exposure Routes: inhalation, skin absorption, ingestion, skin and/or eye contact Symptoms: Irritation eyes, skin, respiratory system; confusion, drowsiness, dizziness, nausea, analgesia, anesthesia; cardiac arrhythmias; liver, kidney damage; decreased audio-visual performance Target Organs: Eyes, skin, respiratory system, cardiovascular system, central nervous system, liver, kidneys, reproductive system (NIOSH, 2016)

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations as needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Minimize physical activity and provide a quiet atmosphere. Monitor for pulmonary edema and treat if necessary . Anticipate seizures and treat if necessary . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport . Do not use emetics. Rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal . Treat frostbite with rapid rewarming techniques . Chlorinated fluorocarbons (CFCs) and related compounds

Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.

Literature sources indicate that this chemical is nonflammable. (NTP, 1992)

In case of fire in the surroundings, use appropriate extinguishing media. In case of fire: keep drums, etc., cool by spraying with water.

Personal protection: self-contained breathing apparatus. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

Personal protection: self-contained breathing apparatus. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

Ventilation. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place. (Extra personal protection: self-contained breathing apparatus).

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Keep in the dark. Ventilation along the floor.Store below 40 deg C (104 deg F), preferably between 15 and 30 deg C (59 and 86 deg F), unless otherwise specified by manufacturer. Store in a tight, light resistant container.

TLV: 50 ppm as TWA; A4 (not classifiable as a human carcinogen).MAK: 41 mg/m3, 5 ppm; peak limitation category: II(8); pregnancy risk group: B

no data available

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

Wear safety goggles or eye protection in combination with breathing protection.

Protective gloves.

Use ventilation, local exhaust or breathing protection.

no data available

Decomposes on heating. This produces toxic and corrosive fumes including hydrogen bromide, hydrogen chloride and hydrogen fluoride. Decomposes under the influence of light.

Sensitive to light, may be stabilized with 0.01% thymol.

Non-flammableThe vapour is heavier than air.HALOTHANE is sensitive to exposure to light. Incompatible with oxidizing materials. Tarnishes or corrodes most metals, with the exception of chromium, nickel and titanium. When moisture is present, it attacks aluminum, brass and lead, but not copper. Contact causes rubber and some plastics to deteriorate rapidly. (NTP, 1992)

no data available

Some plastics and rubber are soluble in halothane and will deteriorate rapidly in contact with halothane vapor or liquid.

Halothane is decomposed by sunlight and should be stored in dark colored bottles.

no data available

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A4; Not classifiable as a human carcinogen.

no data available

The substance is irritating to the eyes. The substance may cause effects on the central nervous system and cardiovascular system. Exposure at high levels could cause unconsciousness.

The substance defats the skin, which may cause dryness or cracking. The substance may have effects on the liver. This may result in liver impairment. Animal tests show that this substance possibly causes toxicity to human reproduction or development.

A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C.

no data available

An estimated BCF of 12 was calculated for 2-bromo-2-chloro-1,1,1-trifluoroethane(SRC), using a measured log Kow of 2.3(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

The Koc of 2-bromo-2-chloro-1,1,1-trifluoroethane is estimated as 425(SRC), using a measured log Kow of 2.3(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that 2-bromo-2-chloro-1,1,1-trifluoroethane is expected to have moderate mobility in soil(SRC).

no data available

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

ADR/RID: no data available

IMDG: no data available

IATA: no data available

ADR/RID: no data available

IMDG: no data available

IATA: no data available

ADR/RID: no data available

IMDG: no data available

IATA: no data available

ADR/RID: no data available

IMDG: no data available

IATA: no data available

ADR/RID: No

IMDG: No

IATA: No

no data available

no data available

0.01% Thymol is used as a stabilizer.High concentrations in the air cause a deficiency of oxygen with the risk of unconsciousness or death.Check oxygen content before entering area.