Caprolactam
Product identifier
- Product name: Caprolactam
- CBnumber: CB8721860
- CAS: 105-60-2
- EINECS Number: 203-313-2
- Synonyms: CAPROLACTAM,Epsilon-caprolactam
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordWarning
Substance
- Product name: Caprolactam
- Synonyms: CAPROLACTAM,Epsilon-caprolactam
- CAS: 105-60-2
- EC number: 203-313-2
- MF: C6H11NO
- MW: 113.16
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx) Combustible.
Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
Further information
No data available
NFPA 704
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 1 | Normally stable, but can become unstable at elevated temperatures and pressures (e.g. propene) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Keep container tightly closed in a dry and well-ventilated place. Store in cool place. hygroscopic
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Appropriate engineering controlsHandle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm Break through time: 480 min
Material tested:Dermatril? (KCL 740 / Aldrich Z677272, Size M)
Splash contact Material: Nitrile rubber
Minimum layer thickness: 0,11 mm Break through time: 480 min
Material tested:Dermatril? (KCL 740 / Aldrich Z677272, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the EC approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Do not let product enter drains.
Information on basic physicochemical properties
- Appearancecolorless crystalline
- OdourNo data available
- Odour ThresholdNo data available d) pH 7,0 - 8,5 at 333 g/l Melting point/freezing point Initial boiling point and boiling range Melting point/range: 68 - 71 °C - lit. 136 - 138 °C at 13 hPa - lit. Flash point 152 °C - closed cup Evaporation rate No data available Flammability (solid, gas) Upper/lower flammability or explosive limits No data available Upper explosion limit: 11,9 %(V) Lower explosion limit: 1,6 %(V) Vapour pressure 9 hPa at 60 °C< 0,01 hPa at 20 °C Vapour density No data available Relative density 1,020 g/cm3 at 75 °C Water solubility soluble Partition coefficient: log Pow: 0,12 at 25 °C n-octanol/water Autoignition temperature Decomposition temperature No data available No data available Viscosity No data available Explosive properties No data available Oxidizing properties No data available
- Melting point/freezing pointMelting point/range: 68 - 71 °C - lit.
- Initial boiling point and boiling range 136 - 138 °C at 13 hPa - lit.
- Flash point152 °C - closed cup
- Evaporation rate152 °C
- Flammability (solid, gas)No data available
- Upper/lower flammability or explosive limits Upper explosion limit: 11,9 %(V) Lower explosion limit: 1,6 %(V)
- Vapour pressure 9 hPa at 60 °C< 0,01 hPa at 20 °C
- Vapour density <0.01 mm Hg ( 20 °C)
- Relative density1,020 g/cm3 at 75 °C
- Water solubilitysoluble
- Partition coefficient: n-octanol/waterlog Pow: 0,12 at 25 °C
- Autoignition temperatureNo data available
- Decomposition temperatureNo data available
- ViscosityNo data available
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
Other safety information
Bulk density 0,50 - 0,55 g/l
Reactivity
No data available
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
No data available
Conditions to avoid
hygroscopic
Incompatible materials
Strong oxidizing agents, Strong bases
Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen oxides (NOx)
Other decomposition products - No data available In the event of fire: see section 5
Information on toxicological effects
Acute toxicityRemarks: Sense Organs and Special Senses (Nose, Eye, Ear, and Taste):Eye:Chromodacryorrhea. Behavioral:Convulsions or effect on seizure threshold. Nutritional and Gross Metabolic:Changes in:Body temperature decrease.
LC50 Inhalation - Rat - 300 mg/m3 LC50 Inhalation - Mouse - 450 mg/m3
Remarks: Behavioral:Muscle contraction or spasticity. LD50 Dermal - Rat - > 2.000 mg/kg
Result: Mild skin irritation - 24 h
Result: Moderate eye irritation - 24 h Eyes - Rabbit
Result: Moderate eye irritation - 24 h
IARC: No ingredient of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Convulsions, To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Toxicity
IC50 - Desmodesmus subspicatus (green algae) - 130 mg/l - 72 h Remarks: (IUCLID)(ε-caprolactam)
Persistence and degradability
No data available
Bioaccumulative potential
No data available
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
No data available
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Waste material must be disposed of in accordance with the Directive on waste 2008/98/EC as well as other national and local regulations. Leave chemicals in original containers. No mixing with other waste. Handle uncleaned containers like the product itself.
IncompatibilitiesCaprolactum decomposes on heating, and on burning producing toxic fumes including nitrogen oxides, ammonia. Reacts violently with strong oxidizers, producing toxic fumes. Toxic decomposition above 400C
Waste DisposalControlled incineration (oxides of nitrogen are removed from the effluent gas by scrubbers and/or thermal devices). Also, Caprolactam may be recovered from Caprolactam still bottoms or nylon waste
Contaminated packaging
Dispose of as unused product.
UN number
ADR/RID: - IMDG: - IATA: -
UN proper shipping name
Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -
Packaging group
ADR/RID: - IMDG: - IATA: -
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
Further information
Not classified as dangerous in the meaning of transport regulations.
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
Other Information
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.