122883-93-6 - Safety Data Sheet

Chemical Safety Data Sheet MSDS / SDS

Revision Date:2026-03-21Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

CBnumber: CB62131294
CAS: 122883-93-6

Relevant identified uses of the substance or mixture and uses advised against

Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
Uses advised against: none

Company Identification

Company: Chemicalbook
Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

Signal wordDanger

Precautionary statements

P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233 Keep container tightly closed.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

Hazard statements

H225 Highly Flammable liquid and vapour

H370 Causes damage to organs

SECTION 3: Composition/information on ingredients

Substance

Product name: Ziprasidone Hydrochloride
Synonyms: CP-88059 HCl;CP88059 hydrochloride
CAS: 122883-93-6
EC number: 602-903-0
MF: C21H21ClN4OS
MW: 412.943

SECTION 4: First aid measures

4.1 Description of first-aid measures

General advice

First aiders need to protect themselves. Show this material safety data sheet to the doctor in attendance.

If inhaled

After inhalation: fresh air. Immediately call in physician. If breathing stops: immediately apply artificial respiration, if necessary also oxygen.

In case of skin contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Call a physician immediately.

In case of eye contact

After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.

If swallowed

After swallowing: fresh air. Make victim drink ethanol (e.g. 1 drinking glass of a 40% alcoholic beverage). Call a doctor immediately (mention methanol ingestion). Only in exceptional cases, if no medical care is available within one hour, induce vomiting (only in fully conscious persons) and make victim drink ethanol again (approx. 0.3 ml of a 40% alcoholic beverage/kg body weight/hour).

4.2 Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11

4.3 Indication of any immediate medical attention and special treatment needed

No data available

4.4 Notes to physician

No data available

SECTION 5: Firefighting measures

5.1 Extinguishing media

Suitable extinguishing media

Water Foam Carbon dioxide (CO2) Dry powder

Unsuitable extinguishing media

For this substance/mixture no limitations of extinguishing agents are given.

5.2 Special hazards arising from the substance or mixture

Carbon oxides
Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire.
Forms explosive mixtures with air at ambient temperatures.

5.3 Advice for firefighters

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.

6.2 Environmental precautions

Do not let product enter drains. Risk of explosion.

6.3 Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb®). Dispose of properly. Clean up affected area.

6.4 Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling

Advice on safe handling

Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.

Advice on protection against fire and explosion

Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.

Hygiene measures

Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Storage conditions

Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition. Keep locked up or in an area accessible only to qualified or authorized persons.

Storage stabilityRecommended storage temperature

-70 °C

Storage class

Storage class (TRGS 510): 3: Flammable liquids

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Ingredients with workplace control parameters

['Component', 'CAS-No.', 'Value', 'Control\nparameters', 'Basis']	['Methanol', '67-56-1', 'PC-TWA', '25 mg/m3', 'Occupational exposure limits for\nhazardous agents in the\nworkplace - Chemical\nhazardous agents.']	['', 'Remarks', 'Skin', None, None]	['', '', 'PC-STEL', '50 mg/m3', 'Occupational exposure limits for\nhazardous agents in the\nworkplace - Chemical\nhazardous agents.']	['', '', 'Skin', None, None]

Biological occupational exposure limits

['Component', 'CAS-No.', 'Parameters', 'Value', 'Biological\nspecimen', 'Basis']	['Methanol', '67-56-1', 'Methanol', '15 mg/l', 'Urine', 'ACGIH -\nBiological\nExposure Indices\n(BEI)']	['', 'Remarks', 'End of shift (As soon as possible after exposure ceases)', None, None, None]

8.2 Exposure controls

Appropriate engineering controls

Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.

Personal protective equipment

Eye/face protection

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Skin protection

required

Body Protection

Flame retardant antistatic protective clothing.

Respiratory protection

required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.

Control of environmental exposure

Do not let product enter drains. Risk of explosion.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

a) Physical stateliquid
b) Colorcolorless
c) Odorpungent
d) Melting point/freezing pointMelting point/range: -98.0 °C
e) Initial boiling point and boiling range64.0 - 65.0 °C at 1013 hPa
f) Flammability (solid, gas)No data available
g) Upper/lower flammability or explosive limitsUpper explosion limit: 36 %(V)
Lower explosion limit: 6 %(V)
h) Flash point9.7 °C - closed cup
i) Autoignition temperature455.0 °C at 1,013 hPa
j) Decomposition temperatureNo data available
k) pHNo data available
l) ViscosityViscosity, kinematic: No data available
Viscosity, dynamic: No data available
m) Water solubilityat 20 °C completely miscible
n) Partition coefficient n-octanol/waterlog Pow: -0.77
o) Vapor pressure130.3 hPa at 20.0 °C 546.6 hPa at 50.0 °C 169.27 hPa at 25.0 °C
p) Density0.79 g/cm3 at 20 °C
Relative densityNo data available
q) Relative vapor densityNo data available
r) Particle characteristicsNo data available
s) Explosive propertiesNot explosive
t) Oxidizing propertiesThe substance or mixture is not classified as oxidizing.

9.2 Other safety information

Minimum ignition energy

0.14 mJ

Conductivity

< 1 µS/cm

Relative vapor density

1.11

SECTION 10: Stability and reactivity

10.1 Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

10.2 Possibility of hazardous reactions

No data available

10.3 Conditions to avoid

Heat, flames and sparks.
Warming.

10.4 Incompatible materials

Acid chlorides, Acid anhydrides, Oxidizing agents, Alkali metals, Reducing agents, Acids

10.5 Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Mixture Acute toxicity

Acute toxicity estimate Oral - 100.11 mg/kg (Calculation method)
Acute toxicity estimate Inhalation - 4 h - 3.1 mg/l - vapor(Calculation method)
Acute toxicity estimate Dermal - 300.13 mg/kg (Calculation method)

Skin corrosion/irritation

Classified based on available data. For more details, see section 2

Serious eye damage/eye irritation

Classified based on available data. For more details, see section 2

Respiratory or skin sensitization

Classified based on available data. For more details, see section 2

Germ cell mutagenicity

Classified based on available data. For more details, see section 2

Carcinogenicity

Classified based on available data. For more details, see section 2

Reproductive toxicity

Classified based on available data. For more details, see section 2

Specific target organ toxicity - single exposure

Mixture causes damage to organs. - Eyes, Central nervous system

Specific target organ toxicity - repeated exposure

Classified based on available data. For more details, see section 2

Aspiration hazard

Classified based on available data. For more details, see section 2

11.2 Additional Information

Methyl alcohol may be fatal or cause blindness if swallowed.
Effects due to ingestion may include:, Headache, Dizziness, Drowsiness, metabolic acidosis,
Coma, Seizures.
Symptoms may be delayed., Damage of the:, Liver, Kidney
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.

Components Methanol

Acute toxicity

Acute toxicity estimate Oral - 100.1 mg/kg (Expert judgment)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Symptoms: Nausea, Vomiting
Acute toxicity estimate Inhalation - 4 h - 3.1 mg/l - vapor (Expert judgment)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Symptoms: Irritation symptoms in the respiratory tract.
Acute toxicity estimate Dermal - 300.1 mg/kg (Expert judgment)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)

Skin corrosion/irritation

Skin - Rabbit
Result: No skin irritation
Remarks: (ECHA)
Remarks: Drying-out effect resulting in rough and chapped skin.

Serious eye damage/eye irritation

Eyes - Rabbit
Result: No eye irritation
Remarks: (ECHA)

Respiratory or skin sensitization

Sensitisation test: - Guinea pig
Result: negative (OECD Test Guideline 406)

Germ cell mutagenicity

Based on available data the classification criteria are not met.
Test Type: Ames test
Test system: Salmonella typhimurium
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster lung cells
Result: negative
Method: OECD Test Guideline 474
Species: Mouse - male and female - Bone marrow
Result: negative

Carcinogenicity

Did not show carcinogenic effects in animal experiments.

Reproductive toxicity

Based on available data the classification criteria are not met.

Specific target organ toxicity - single exposure

Causes damage to organs. - Eyes, Central nervous system
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Acute oral toxicity - Nausea, Vomiting
Acute inhalation toxicity - Irritation symptoms in the respiratory tract.

Specific target organ toxicity - repeated exposure

Classified based on available data. For more details, see section 2

Aspiration hazard

Classified based on available data. For more details, see section 2

SECTION 12: Ecological information

12.1 Toxicity

Mixture

No data available

12.2 Persistence and degradability

No data available

12.3 Bioaccumulative potential

No data available

12.4 Mobility in soil

No data available

12.5 Results of PBT and vPvB assessment

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

12.6 Endocrine disrupting properties

No data available

12.7 Other adverse effects

No data available

Components Methanol

Toxicity to fish flow-through test LC50 - Lepomis macrochirus (Bluegill) - 15,400.0 mg/l - 96 h (US-EPA)
Toxicity to daphnia semi-static test EC50 - Daphnia magna (Water flea) - 18,260 and other aquatic mg/l - 96 h invertebrates (OECD Test Guideline 202)
Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata (green algae) - ca. 22,000.0 mg/l - 96 h (OECD Test Guideline 201)
Toxicity to bacteria static test IC50 - activated sludge - > 1,000 mg/l - 3 h (OECD Test Guideline 209)
Toxicity to NOEC - Oryzias latipes (Orange-red killifish) - 7,900 mg/l - 200 fish(Chronic toxicity) h
Remarks: (External MSDS)

SECTION 13: Disposal considerations

13.1 Waste treatment methods

Product
Offer surplus and non-recyclable solutions to a licensed disposal company.

SECTION 14: Transport information

14.1 UN number

ADR/RID: 1230
IMDG: 1230
IATA-DGR: 1230

14.2 UN proper shipping name

ADR/RID: METHANOL,SOLUTION
IMDG: METHANOL,SOLUTION
IATA-DGR: Methanol,SOLUTION

14.3 Transport hazard class(es)

ADR/RID: 3 (6.1)
IMDG: 3 (6.1)
IATA-DGR: 3 (6.1)

14.4 Packaging group

ADR/RID: II
IMDG: II
IATA-DGR: II

14.5 Environmental hazards

ADR/RID: no
IMDG Marine pollutant: no
IATA-DGR: no

14.6 Special precautions for user

Based on chemical properties, choose appropriate tools and conditions of transport.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.

14.7 Incompatible materials

Acid chlorides, Acid anhydrides, Oxidizing agents, Alkali metals, Reducing agents, Acids

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture

National regulatory information
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Measures on the Environmental Administration of New Chemical Substances Registration
Registration/Notification number : B1A222220064
Downstream users need to comply with the conditions of safe use of the chemical, understand the environmental and health hazard and risk management measures identified on the SDS as well as the local/national regulations concerning the chemical.
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.

SECTION 16: Other information

Abbreviations and acronyms

CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration

Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.