Chemical Safety Data Sheet MSDS / SDS
Cremophor EL
Revision Date:2026-04-11Revision Number:1
Product identifier
- Product name: Cremophor EL
- CBnumber: CB0750518
- CAS: 61791-12-6
- EINECS Number: 500-151-7
- Synonyms: Cremophor EL,Polyoxyethylene Castor Oil
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordWarning
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P264 Wash skin thouroughly after handling.
Hazard statements
H319 Causes serious eye irritation
Substance
- Product name: Cremophor EL
- Synonyms: Cremophor EL,Polyoxyethylene Castor Oil
- CAS: 61791-12-6
- EC number: 500-151-7
- MF: NULL
4.1 Description of first-aid measures
If inhaledAfter inhalation: fresh air.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.
In case of eye contact
After eye contact: rinse out with plenty of water. Remove contact lenses.
If swallowed
After swallowing: make victim drink water (two glasses at most). Consult doctor if feeling unwell.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
4.4 Notes to physician
No data available
5.1 Extinguishing media
Suitable extinguishing mediaWater Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Combustible.
Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.
Combustible.
Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.
5.3 Advice for firefighters
In the event of fire, wear self-contained breathing apparatus.
Prevent fire extinguishing water from contaminating surface water or the ground water system.
Prevent fire extinguishing water from contaminating surface water or the ground water system.
6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb® ).
Dispose of properly. Clean up affected area.
Dispose of properly. Clean up affected area.
6.4 Reference to other sections
For disposal see section 13.
7.1 Precautions for safe handling
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditionsTightly closed.
Recommended storage temperature see product label.
Storage class
Recommended storage temperature see product label.
Storage class (TRGS 510): 10: Combustible liquids
8.1 Control parameters
Ingredients with workplace control parametersContains no substances with occupational exposure limit values.
8.2 Exposure controls
Appropriate engineering controlsChange contaminated clothing. Wash hands after working with substance.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
not required
Respiratory protection
Not required; except in case of aerosol formation.
Control of environmental exposure
Do not let product enter drains.
Information on basic physicochemical properties
- a) Physical stateliquid
- b) Colorlight yellow
- c) Odorat 100.00%. bland
- d) Melting point/freezing pointNo data available
- e) Initial boiling point and boiling range232.6℃[at 101 325 Pa]
- f) Flammability (solid, gas)No data available
- g) Upper/lower flammability or explosive limitsNo data available
- h) Flash point257℃
- i) Autoignition temperatureNo data available
- j) Decomposition temperatureca. 300 °C
- k) pH6 - 8 at 100 g/l at 20 °C
- l) ViscosityViscosity, kinematic: No data available
Viscosity, dynamic: 700 - 800 mPa.s at 25 °C - m) Water solubility100 g/l at 20 °C
- n) Partition coefficient n-octanol/waterNo data available
- o) Vapor pressure0Pa at 25℃
- p) Density1.050 g/cm3
- Relative density1.05 g/mL at 20 °C
- q) Relative vapor densityNo data available
- r) Particle characteristicsNo data available
- s) Explosive propertiesNo data available
- t) Oxidizing propertiesNo data available
- SolubilityChloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
9.2 Other safety information
No data available
10.1 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.2 Possibility of hazardous reactions
no information available
10.3 Conditions to avoid
Strong heating.
10.4 Incompatible materials
No data available
10.5 Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Acute toxicityLD50 Oral - Rat - > 5,000 mg/kg
Inhalation: No data available
Dermal: No data available
Skin corrosion/irritation
Inhalation: No data available
Dermal: No data available
Skin - Rabbit
Result: No skin irritation
Serious eye damage/eye irritation
Result: No skin irritation
Remarks: No data available
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Tests on bacterial or mammalian cell cultures did not show mutagenic effects.
Carcinogenicity
Animal testing did not show any carcinogenic effects.
Reproductive toxicity
Did not show teratogenic effects in animal experiments.
Animal testing did not show any effects on fertility.
Specific target organ toxicity - single exposure
Animal testing did not show any effects on fertility.
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
Classified based on available data. For more details, see section 2
12.1 Toxicity
Toxicity to fish LC50 - Leuciscus idus (Golden orfe) - 448 mg/l - 48 h (DIN 38412)
Toxicity to daphnia EC50 - Daphnia magna (Water flea) - > 100 mg/l - 48 h and other aquatic (OECD Test Guideline 202) invertebrates
Toxicity to algae EC50 - Desmodesmus subspicatus (green algae) - > 93 mg/l - 72 h (OECD Test Guideline 201)
Toxicity to daphnia EC50 - Daphnia magna (Water flea) - > 100 mg/l - 48 h and other aquatic (OECD Test Guideline 202) invertebrates
Toxicity to algae EC50 - Desmodesmus subspicatus (green algae) - > 93 mg/l - 72 h (OECD Test Guideline 201)
12.2 Persistence and degradability
Biodegradability aerobic - Exposure time 21 d
Result: 90 - 100 % - Biodegradable (OECD Test Guideline 302)
Remarks: According to the results of tests of biodegradability this product is considered as being readily biodegradable.
Result: 90 - 100 % - Biodegradable (OECD Test Guideline 302)
Remarks: According to the results of tests of biodegradability this product is considered as being readily biodegradable.
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Endocrine disrupting properties
No data available
12.7 Other adverse effects
No data available
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Offer surplus and non-recyclable solutions to a licensed disposal company.
14.1 UN number
ADR/RID: -
IMDG: -
IATA-DGR: -
IMDG: -
IATA-DGR: -
14.2 UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA-DGR: Not dangerous goods
IMDG: Not dangerous goods
IATA-DGR: Not dangerous goods
14.3 Transport hazard class(es)
ADR/RID: -
IMDG: -
IATA-DGR: -
IMDG: -
IATA-DGR: -
14.4 Packaging group
ADR/RID: -
IMDG: -
IATA-DGR: -
IMDG: -
IATA-DGR: -
14.5 Environmental hazards
ADR/RID: no
IMDG Marine pollutant: no
IATA-DGR: no
IMDG Marine pollutant: no
IATA-DGR: no
14.6 Special precautions for user
14.7 Incompatible materials
Further information: Not classified as dangerous in the meaning of transport regulations.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
National regulatory information
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.