ChemicalBook
Chemical Safety Data Sheet MSDS / SDS

Dicloxacillin

Revision Date:2026-03-21Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: Dicloxacillin
  • CBnumber: CB6704937
  • CAS: 3116-76-5
  • EINECS Number: 221-488-3
  • Synonyms: dicloxacilin ;Dicloxacilina

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS) No data available
  • Signal wordNo data available
Precautionary statements
No data available
Hazard statements
No data available

SECTION 3: Composition/information on ingredients

Substance

  • Product name: Dicloxacillin
  • Synonyms: dicloxacilin ;Dicloxacilina
  • CAS: 3116-76-5
  • EC number: 221-488-3
  • MF: C19H17Cl2N3O5S
  • MW: 470.33

SECTION 4: First aid measures

4.1 Description of necessary first-aid measures

General advice
no data available
If inhaled
Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Following skin contact
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Following eye contact
Rinse with pure water for at least 15 minutes. Consult a doctor.
Following ingestion
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control
Center immediately.

4.2 Most important symptoms/effects, acute and delayed

Absorption, Distribution and Excretion Absorption of the isoxazolyl penicillins after oral administration is rapid but incomplete: peak blood levels are achieved in 1-1.5 hours. Oral absorption of cloxacillin, dicloxacillin, oxacillin and nafcillin is delayed when the drugs are administered after meals.

4.3 Indication of immediate medical attention and special treatment needed, if necessary

no data available

SECTION 5: Firefighting measures

5.1 Extinguishing media

Use dry chemical, carbon dioxide or alcohol-resistant foam.

5.2 Specific hazards arising from the chemical

no data available

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.

6.2 Environmental precautions

Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.

6.3 Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark- proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

SECTION 7: Handling and storage

7.1 Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

7.2 Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values
no data available
Biological limit values
no data available

8.2 Appropriate engineering controls

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the riskelimination area.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection
Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Skin protection
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Respiratory protection
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
Thermal hazards
no data available

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • Particle characteristicsno data available
  • Relative vapour densityno data available
  • Density and/ or relative density1.62 g/cm3
  • Vapour pressureno data available
  • N-octanol-water partition coefficientno data available
  • SolubilityH2O: Insoluble,
    DMSO: Soluble,
  • Kinematic viscosityno data available
  • pHno data available
  • Decomposition temperatureno data available
  • Auto-ignition temperatureno data available
  • Flash point372.5°C
  • Lower and upper explosion limit/flammability limitno data available
  • Flammabilityno data available
  • Boilingpoint or initial boiling point and boiling range692.4°C at 760 mmHg
  • Melting point/ freezing pointno data available
  • Odourno data available
  • Colorno data available
  • Physical stateSolid
  • Water solubility3.63 mg/L

SECTION 10: Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Quite stable @ acidic ph; stable @ room temp sodium

10.3 Possibility of hazardous reactions

no data available

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

no data available

10.6 Hazardous decomposition products

no data available

SECTION 11: Toxicological information

Acute toxicity

Oral
no data available
Inhalation
no data available
Dermal
no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

no data available

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

SECTION 12: Ecological information

12.1 Toxicity

Toxicity to fish
no data available
Toxicity to daphnia and other aquatic invertebrates
no data available
Toxicity to algae
no data available
Toxicity to microorganisms
no data available

12.2 Persistence and degradability

no data available

12.3 Bioaccumulative potential

no data available

12.4 Mobility in soil

no data available

12.5 Other adverse effects

no data available

SECTION 13: Disposal considerations

13.1 Disposal methods

Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing.
Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

SECTION 14: Transport information

14.1 UN Number

no data available

14.2 UN Proper Shipping Name

no data available

14.3 Transport hazard class(es)

no data available

14.4 Packing group, if applicable

no data available

14.5 Environmental hazards

no data available

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to IMO instruments

no data available

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

European Inventory of Existing Commercial Chemical Substances (EINECS)
Listed.
EC Inventory
Listed.
United States Toxic Substances Control Act (TSCA) Inventory
Not Listed.
China Catalog of Hazardous chemicals 2015
Not Listed.
New Zealand Inventory of Chemicals (NZIoC)
Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS)
Not Listed.
Vietnam National Chemical Inventory
Not Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC)
Not Listed.
Korea Existing Chemicals List (KECL)
Not Listed.

SECTION 16: Other information

Abbreviations and acronyms

• CAS: Chemical Abstracts Service
• ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
• RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
• IMDG: International Maritime Dangerous Goods
• IATA: International Air Transportation Association
• TWA: Time Weighted Average
• STEL: Short term exposure limit
• LC50: Lethal Concentration 50%
• LD50: Lethal Dose 50%
• EC50: Effective Concentration 50%

References

IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/ eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.
org/echemportal/index?pageID=0&request_locale=en
CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.
gov/hazmat/library/erg
Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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