ChemicalBook
Chemical Safety Data Sheet MSDS / SDS

Grubbs catalyst 2nd generation

Revision Date:2026-03-21Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: Grubbs catalyst 2nd generation
  • CBnumber: CB4322469
  • CAS: 246047-72-3
  • EINECS Number: 688-322-3
  • Synonyms: GRUBBS II;Grubbs 2nd

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordWarning
Precautionary statements
P370+P378 In case of fire: Use … for extinction.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P240 Ground/bond container and receiving equipment.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
Hazard statements
H228 Flammable solid

SECTION 3: Composition/information on ingredients

Substance

  • Product name: Grubbs catalyst 2nd generation
  • Synonyms: GRUBBS II;Grubbs 2nd
  • CAS: 246047-72-3
  • EC number: 688-322-3
  • MF: C46H65Cl2N2PRu
  • MW: 848.98

SECTION 4: First aid measures

General advice

Show this safety data sheet to the doctor in attendance.

If inhaled

After inhalation: fresh air.

In case of skin contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.

In case of eye contact

After eye contact: rinse out with plenty of water. Remove contact lenses.

If swallowed

After swallowing: make victim drink water (two glasses at most). Consult doctor if feeling unwell.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11

Protection of first-aiders

For personal protection see section 8.

Notes to physician

No data available

SECTION 5: Firefighting measures

Suitable extinguishing media

Water Foam Carbon dioxide (CO2) Dry powder

Unsuitable extinguishing media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards during fire fighting

Combustible. Development of hazardous combustion gases or vapours possible in the event of fire.

Hazardous combustion products

Carbon oxides Nitrogen oxides (NOx) Oxides of phosphorus Hydrogen chloride gas Ruthenium oxide

Specific extinguishing methods

Suppress (knock down) gases/vapours/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.

Special protective equipment for fire-fighters

In the event of fire, wear self-contained breathing apparatus.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition. Evacuate the danger area, observe emergency procedures, consult an expert. Advice for emergency responders: For personal protection see section 8.

Environmental precautions

Do not let product enter drains. Risk of explosion.

Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dusts.

SECTION 7: Handling and storage

Handling

Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharge.
Avoidance of contact
Strong oxidizing agents

Storage

Further information on storage conditions
Tightly closed. Keep away from heat and sources of ignition.
Storage class
4.1B, Flammable solid hazardous materials
Recommended storage temperature
2 - 8 °C
Further information on storage stability
Handle and store under inert gas. Air sensitive. Light sensitive.
Packaging material
Suitable material: Amber Glass Bottle/Jar

SECTION 8: Exposure controls/personal protection

Ingredients with workplace control parameters

Contains no substances with occupational exposure limit values.

Engineering measures

No data available

Personal protective equipment

Respiratory protection
required when dusts are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type
Filter type P1
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Safety glasses
Skin and body protection
Flame retardant antistatic protective clothing.
Hand protection
Material
Nitrile rubber
Break through time
480 min
Glove thickness
0.11 mm
Protective index
Full contact
Manufacturer
(KCL 740 / Aldrich Z677272, Size M)
Material
Nitrile rubber
Break through time
480 min
Glove thickness
0.11 mm
Protective index
Splash contact
Manufacturer
(KCL 740 / Aldrich Z677272, Size M)
Manufacturer
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374
Remarks
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Hygiene measures
Change contaminated clothing. Wash hands after working with substance.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • SolubilityChloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Very Slightly, Heated)
  • Physical stateSolid
  • Vapor pressureNo data available
  • Relative vapor densityNo data available
  • Relative densityNo data available
  • DensityNo data available
  • Water solubilityNo data available
  • Partition coefficient: n-octanol/waterNo data available
  • Particle characteristics Particle sizeNo data available
  • Molecular weight848.97 g/mol
  • Oxidizing propertiesnone
  • Explosive propertiesNot classified as explosive.
  • Flow timeNo data available
  • Viscosity, kinematicNo data available
  • Viscosity, dynamicNo data available
  • Decomposition temperatureNo data available
  • Autoignition temperatureNo data available
  • Lower explosion limit / Lower flammability limitNo data available
  • Upper explosion limit / Upper flammability limitNo data available
  • Burning rateNo data available
  • Flammability (liquids)No data available
  • Flammability (solid, gas)The substance or mixture is a flammable solid with the category 2.
  • Evaporation rateNo data available
  • Flash pointNot applicable
  • Boiling point/boiling rangeNo data available
  • Melting point/ range143.5 - 148.5 °C
  • pHNo data available
  • Odor ThresholdNo data available
  • OdorNo data available
  • Colorpink, brown
  • Appearancecrystalline

SECTION 10: Stability and reactivity

Reactivity

The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

Possibility of hazardous reactions

No data available

Conditions to avoid

Air no information available

Incompatible materials

Strong oxidizing agents

Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Acute toxicity
Oral: No data available
Inhalation: No data available
Dermal: No data available
Skin corrosion/irritation
Classified based on available data. For more details, see section 2
Serious eye damage/eye irritation
Classified based on available data. For more details, see section 2
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2

11.2 Additional Information

To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.

SECTION 12: Ecological information

Ecotoxicity

No data available

Persistence and degradability

No data available

Bioaccumulative potential

No data available

Mobility in soil

No data available

Other adverse effects

No data available

SECTION 13: Disposal considerations

Disposal methods

Waste from residues
Offer surplus and non-recyclable solutions to a licensed disposal company.

SECTION 14: Transport information

International Regulations

IATA-DGR

UN/ID No. : UN 1325
Proper shipping name : Flammable solid, organic, n.o.s.
(Ruthenium, [1,3-bis(2,4,6-trimethylphenyl)-2imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphi ne)-, (SP-5-41)-)
Class : 4.1
Packing group : III
Labels : Division 4.1 - Flammable solids
Packing instruction (cargo aircraft) : 449
Packing instruction (passenger aircraft) : 446

IMDG-Code

UN number : UN 1325
Proper shipping name : FLAMMABLE SOLID, ORGANIC, N.O.S.
(Ruthenium, [1,3-bis(2,4,6-trimethylphenyl)-2imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphi ne)-, (SP-5-41)-)
Class : 4.1
Packing group : III
Labels : 4.1
EmS Code : F-A, S-G
Marine pollutant : no

Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

Not applicable for product as supplied.

National Regulations

JT/T 617

UN number : UN 1325
Proper shipping name : FLAMMABLE SOLID, ORGANIC, N.O.S.
(Ruthenium, [1,3-bis(2,4,6-trimethylphenyl)-2imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphi ne)-, (SP-5-41)-)
Class : 4.1
Packing group : III
Labels : 4.1
Environmentally hazardous : no

Special precautions for user

The transport classification(s) provided herein are for informational purposes only, and solely based upon the properties of the unpackaged material as it is described within this Safety Data Sheet. Transportation classifications may vary by mode of transportation, package sizes, and variations in regional or country regulations.

SECTION 15: Regulatory information

Catalogue of Hazardous Chemicals : This product is not listed in the catalogue of hazardous chemicals, but it meets the definition of hazardous chemicals and its principles of determination.
Downstream users need to comply with the conditions of safe use of the chemical, understand the environmental and health hazard and risk management measures identified on the SDS as well as the local/national regulations concerning the chemical.

National regulatory information

Regulations on Safety Management of Hazardous Chemicals

Identification of Major Hazard Installations for Hazardous Chemicals (GB 18218)

Not listed

Hazardous Chemicals for Priority Management

Not listed under SAWS

Catalogue of Specially Controlled Hazardous

Not listed Chemicals

List of Explosive Precursors

Not listed

Regulations on Labour Protection in Workplaces where Toxic Substances are Used

Catalogue of Highly Toxic Chemicals

Not listed

Regulation of Environmental Management on the First Import of Chemicals and the Import and Export of Toxic Chemicals

China Severely Restricted Toxic Chemicals for Import and Export

Not listed

Measures on the Environmental Administration of New Chemical Substances Registration

Registration/Notification number

B1A222221991

Regulation on the Administration of Precursor Chemicals

Catalogue and Classification of Precursor Chemicals

Not listed

Regulations on the Administration of Controlled Chemicals

List of Controlled Chemicals

Not listed

Regulations of Ozone Depleting Substances Management

List of Controlled Ozone Depleting Substances

Not listed

List of Controlled Ozone Depleting Substances Import and Export

Not listed

Environmental Protection Law

List of Priority Controlled Chemicals

Not listed

List of Key Controlled New Pollutants

Not listed

SECTION 16: Other information

Full text of other abbreviations

AIIC - Australian Inventory of Industrial Chemicals
ANTT - National Agency forTransport by Land of Brazil
ASTM - American Society for the Testing of Materials
bw - Body weight
CMR - Carcinogen, Mutagen or Reproductive Toxicant
DIN -Standard of the German Institute for Standardisation
DSL - Domestic SubstancesList (Canada)
ECx - Concentration associated with x% response
ELx - Loading rate associated with x% response
EmS - Emergency Schedule
ENCS - Existing and NewChemical Substances (Japan)
ErCx - Concentration associated with x% growth rate response
ERG - Emergency Response Guide
GHS - Globally Harmonised System
GLP - Good Laboratory Practice
IARC - International Agency for Research on Can- cer
IATA - International Air Transport Association
IBC - International Code for theConstruction and Equipment of Ships carrying Dangerous Chemicals in Bulk
IC50 -Half maximal inhibitory concentration
ICAO - International Civil Aviation Organiza- tion
IECSC - Inventory of Existing Chemical Substances in China
IMDG - Interna- tional Maritime Dangerous Goods
IMO - International Maritime Organisation
ISHL -Industrial Safety and Health Law (Japan)
ISO - International Organisation forStandardisation
KECI - Korea Existing Chemicals Inventory
LC50 - Lethal Concen- tration to 50 % of a test population
LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose)
MARPOL - International Convention for the Prevention of Pol- lution from Ships
MERCOSUR - The Agreement for the Facilitation of the Transport of Dangerous Goods
n.o.s. - Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC - No Observed (Adverse) Effect Concentration
NO(A)EL - No Observed (Adverse) Ef- fect Level
NOELR - No Observable Effect Loading Rate
NOM - Official MexicanNorm
NTP - National Toxicology Program
NZIoC - New Zealand Inventory of Chem- icals
OECD - Organisation for Economic Co-operation and Development
OPPTS - Of- fice of Chemical Safety and Pollution Prevention
PBT - Persistent, Bioaccumulative and Toxic substance
PICCS - Philippines Inventory of Chemicals and Chemical Sub- stances
(Q)SAR - (Quantitative) Structure Activity Relationship
REACH - Regulation (EC) No 1907/2006 of the European Parliament and of the Council concerning theRegistration, Evaluation, Authorisation and Restriction of Chemicals
SADT - Self-Accelerating Decomposition Temperature
SDS - Safety Data Sheet
TCSI - TaiwanChemical Substance Inventory
TDG - Transportation of Dangerous Goods
TECI -Thailand Existing Chemicals Inventory
TSCA - Toxic Substances Control Act (UnitedStates)
UN - United Nations
UNRTDG - United Nations Recommendations on theTransport of Dangerous Goods
vPvB - Very Persistent and Very Bioaccumulative
WHMIS - Workplace Hazardous Materials Information System
Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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