Chemical Safety Data Sheet MSDS / SDS
Hydrazinium hydroxide solution
Revision Date:2026-04-04Revision Number:1
Product identifier
- Product name: Hydrazinium hydroxide solution
- CBnumber: CB2110460
- CAS: 10217-52-4
- EINECS Number: 206-114-9
- Synonyms: Hydrazine monohydrate,Hydrazinium hydroxide solution
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P273 Avoid release to the environment.
P201 Obtain special instructions before use.
Hazard statements
H410 Very toxic to aquatic life with long lasting effects
H350 May cause cancer
H317 May cause an allergic skin reaction
H314 Causes severe skin burns and eye damage
Substance
- Product name: Hydrazinium hydroxide solution
- Synonyms: Hydrazine monohydrate,Hydrazinium hydroxide solution
- CAS: 10217-52-4
- EC number: 206-114-9
- MF: H4N2
- MW: 32.05
General advice
First aiders need to protect themselves. Show this safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Immediately call in physician. If breathing stops: immediately apply artificial respiration, if necessary also oxygen.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Call a physician immediately.
In case of eye contact
After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: make victim drink water (two glasses at most), avoid vomiting (risk of perforation). Call a physician immediately. Do not attempt to neutralise.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
Protection of first-aiders
For personal protection see section 8.
Notes to physician
No data available
Suitable extinguishing media
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
Specific hazards during fire fighting
Not combustible. Vapours are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating. Ambient fire may liberate hazardous vapours.
Hazardous combustion products
Nitrogen oxides (NOx) Nitrogen oxides (NOx)
Specific extinguishing methods
Suppress (knock down) gases/vapours/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Special protective equipbreathing ment for fire-fighters
Stay in danger area only with self-contained apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapours, aerosols. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert. Advice for emergency responders: For personal protection see section 8.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material . Dispose of properly. Clean up affected area.
Handling
Advice on safe handlingWork under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Avoidance of contact
Oxidizing agents Oxygen Copper Zinc Organic materials
Storage
Further information on storage conditionsTightly closed. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorised persons.
Storage class
6.1C, Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Recommended storage
Recommended storage temperature see product label. temperature
Further information on storage stability
Air sensitive.
control parameter
Hazard composition and occupational exposure limitsDoes not contain substances with occupational exposure limits.
Engineering measures
No data available
Personal protective equipment
Respiratory protectionrequired when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Filter type ABEK
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Eye/face protection
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Tightly fitting safety goggles
Skin and body protection
Tightly fitting safety goggles
protective clothing
Hand protection
Material
Nature latex/chloroprene
Break through time
480 min
Glove thickness
0.6 mm
Protective index
Full contact
Manufacturer
Lapren® (KCL 706 / Aldrich Z677558, Size M)
Material
Nitrile rubber
Break through time
30 min
Glove thickness
0.11 mm
Protective index
Splash contact
Manufacturer
(KCL 740 / Aldrich Z677272, Size M)
Manufacturer
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374
Remarks
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Hygiene measures
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Information on basic physicochemical properties
- Physical stateliquid
- Particle characteristics Particle sizeNo data available
- Oxidizing propertiesNo data available
- Explosive propertiesNo data available
- Flow timeNo data available
- Viscosity, kinematicNo data available
- Viscosity, dynamicNo data available
- Decomposition temperatureNo data available
- Autoignition temperatureNot applicable
- Partition coefficient: n-octanol/waterNo data available
- Colorcolourless
- Appearanceliquid
- Water solubilitysoluble (20 °C)
- Density1.01 g/cm3 (20 °C)
- Relative density1.03 g/mL at 20 °C
- Relative vapor density>1 (vs air)
- Vapor pressure5 mm Hg ( 25 °C)
- Lower explosion limit / Lower flammability limit99.99%
- Upper explosion limit / Upper flammability limit99.99%
- Self-ignitionNot applicable
- Burning rateNo data available
- Flammability (liquids)The product is not flammable.
- Flammability (solid, gas)No data available
- Evaporation rateNo data available
- Flash point100 °C
Method: closed cup Not applicable - Boiling point/boiling range120.1 °C(lit.)
- Melting point/ rangeNo data available
- pHNo data available
- Odor ThresholdNo data available
- OdorNo data available
Reactivity
Forms explosive mixtures with air on intense heating. A range from approx. 15 Kelvin below the flash point is to be rated as critical.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions
Violent reactions possible with: The generally known reaction partners of water.
Conditions to avoid
Strong heating.
Incompatible materials
Oxidizing agents Oxygen Copper Zinc Organic materials
Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Mixture Acute toxicityAcute toxicity estimate Oral - 1,049 mg/kg (Calculation method)
Symptoms: If ingested, severe burns of the mouth and throat, as well as a danger of perforation of the oesophagus and the stomach.
Acute toxicity estimate Inhalation - 4 h - 3.04 mg/l - vapour(Calculation method)
Symptoms: mucosal irritations, Cough, Shortness of breath, Possible damages:, damage of respiratory tract
Acute toxicity estimate Dermal - 1,201 mg/kg (Calculation method)
Skin corrosion/irritation
Symptoms: If ingested, severe burns of the mouth and throat, as well as a danger of perforation of the oesophagus and the stomach.
Acute toxicity estimate Inhalation - 4 h - 3.04 mg/l - vapour(Calculation method)
Symptoms: mucosal irritations, Cough, Shortness of breath, Possible damages:, damage of respiratory tract
Acute toxicity estimate Dermal - 1,201 mg/kg (Calculation method)
Remarks: Mixture causes burns.
Serious eye damage/eye irritation
Remarks: Mixture causes serious eye damage.
Risk of blindness!
Respiratory or skin sensitization
Risk of blindness!
Mixture may cause an allergic skin reaction.
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Possible carcinogen.
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi, pneumonitis, pulmonary edema, burning sensation, Cough, wheezing, laryngitis, Shortness of breath, Headache,
Nausea
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Other dangerous properties can not be excluded.
This substance should be handled with particular care.
Handle in accordance with good industrial hygiene and safety practice.
Components Hydrazine
Nausea
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Other dangerous properties can not be excluded.
This substance should be handled with particular care.
Handle in accordance with good industrial hygiene and safety practice.
Acute toxicity
Oral: No data available
Inhalation: No data available
Acute toxicity estimate Dermal - Not tested on animals - 300.1 mg/kg
Remarks: Expert judgement
Inhalation: No data available
Acute toxicity estimate Dermal - Not tested on animals - 300.1 mg/kg
Remarks: Expert judgement
Skin corrosion/irritation
Skin - Rabbit
Result: Corrosive - 4 h (OECD Test Guideline 404)
Remarks: (55% solution)
Remarks: (Regulation (EC) No 1272/2008, Annex VI)
Result: Corrosive - 4 h (OECD Test Guideline 404)
Remarks: (55% solution)
Remarks: (Regulation (EC) No 1272/2008, Annex VI)
Serious eye damage/eye irritation
Remarks: Causes serious eye damage.
Respiratory or skin sensitization
(Regulation (EC) No 1272/2008, Annex VI)
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Presumed to have carcinogenic potential for humans
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
Ecotoxicity
Toxicity to fishRemarks: No data available
Components:
Hydrazine:
Toxicity to fishLC50 (Poecilia reticulata (guppy)): 0.61 mg/l End point: mortality Exposure time: 96 h Test Type: static test Remarks: (ECHA)
Toxicity to daphnia and other aquatic invertebrates
EC50 (Daphnia pulex (Water flea)): 0.16 mg/l End point: Immobilization Exposure time: 48 h Test Type: semi-static test Analytical monitoring: yes Method: US-EPA Remarks: (in analogy to similar products) The value is given in analogy to the following substances: Hydrazine hydrate
Toxicity to algae/aquatic plants
ErC50 (Desmodesmus subspicatus (green algae)): 0.017 mg/l Exposure time: 48 h Test Type: static test Analytical monitoring: yes Method: Regulation (EC) No. 440/2008, Annex, C.3 GLP: yes
M-Factor (Acute aquatic
1 toxicity)
Toxicity to daphnia and other aquatic invertebrates (Chronic toxicity)
NOEC (Daphnia magna (Water flea)): 0.123 mg/l End point: mortality Exposure time: 21 d Test Type: semi-static test Analytical monitoring: yes Method: OECD Test Guideline 211 GLP: yes
M-Factor (Chronic aquatic toxicity)
1
Toxicity to microorganisms
EC50 (activated sludge): 5.5 mg/l Exposure time: 3 h Test Type: static test Method: OECD Test Guideline 209 GLP: yes
Persistence and degradability
BiodegradabilityRemarks: No data available
Components:
Hydrazine:
Biodegradabilityaerobic Inoculum: activated sludge Concentration: 0.5 mg/l Result: Inherently biodegradable. Biodegradation: 99 % Exposure time: 24 h Method: OECD Test Guideline 302B GLP: yes
Bioaccumulative potential
BioaccumulationRemarks: No data available
Components:
Hydrazine:
BioaccumulationRemarks: No data available
Partition coefficient: noctanol/water
log Pow: -0.16 (25 °C) pH: 7 Method: OECD Test Guideline 107 Remarks: Bioaccumulation is not expected.
Mobility in soil
Stability in soilRemarks: No data available
Components:
Hydrazine:
Stability in soilRemarks: No data available
Other adverse effects
Components:
Hydrazine:
Additional ecological informationNo data available
Disposal methods
Waste from residuesOffer surplus and non-recyclable solutions to a licensed disposal company.
International Regulations
IATA-DGR
UN/ID No. : UN 3293
Proper shipping name : Hydrazine, aqueous solution
Class : 6.1
Packing group : III
Labels : Division 6.1 - Toxic substances
Packing instruction (cargo aircraft) : 663
Packing instruction (passenger aircraft) : 655
Proper shipping name : Hydrazine, aqueous solution
Class : 6.1
Packing group : III
Labels : Division 6.1 - Toxic substances
Packing instruction (cargo aircraft) : 663
Packing instruction (passenger aircraft) : 655
IMDG-Code
UN number : UN 3293
Proper shipping name : HYDRAZINE, AQUEOUS SOLUTION
Class : 6.1
Packing group : III
Labels : 6.1
EmS Code : F-A, S-A
Marine pollutant : yes
Proper shipping name : HYDRAZINE, AQUEOUS SOLUTION
Class : 6.1
Packing group : III
Labels : 6.1
EmS Code : F-A, S-A
Marine pollutant : yes
Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not applicable for product as supplied.
National Regulations
JT/T 617
UN number : UN 3293
Proper shipping name : HYDRAZINE, AQUEOUS SOLUTION
Class : 6.1
Packing group : III
Labels : 6.1
Environmentally hazardous : no
Proper shipping name : HYDRAZINE, AQUEOUS SOLUTION
Class : 6.1
Packing group : III
Labels : 6.1
Environmentally hazardous : no
Special precautions for user
The transport classification(s) provided herein are for informational purposes only, and solely based upon the properties of the unpackaged material as it is described within this Safety Data Sheet. Transportation classifications may vary by mode of transportation, package sizes, and variations in regional or country regulations.
National regulatory information
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals
Hazardous Chemicals for Priority Management
Not applicable under SAWS
Catalogue of Specially Controlled Hazardous
Not listed Chemicals
List of Explosive Precursors
Not listed
Regulation of Environmental Management on the First Import of Chemicals and the Import and Export of Toxic Chemicals
China Severely Restricted Toxic Chemicals for Import and Export
Not applicable
Regulation on the Administration of Precursor Chemicals
Catalogue and Classification of Precursor Chemicals
Not listed
Regulations on the Administration of Controlled Chemicals
List of Controlled Chemicals
Not listed
Regulations of Ozone Depleting Substances Management
List of Controlled Ozone Depleting Substances
Not listed
List of Controlled Ozone Depleting Substances Import and Export
Not listed
Environmental Protection Law
List of Priority Controlled Chemicals
Not listed
List of Key Controlled New Pollutants
Not listed
Full text of other abbreviations
ACGIHUSA. ACGIH Threshold Limit Values (TLV)
GBZ 2.1-2007
Occupational exposure limits for hazardous agents in the workplace - Chemical hazardous agents.
ACGIH / TWA
8-hour, time-weighted average
GBZ 2.1-2007 / PC-TWA
Permissible concentration - time weighted average
GBZ 2.1-2007 / PC-STEL AIIC - Australian Invent Transport by Land of Bra bw - Body weight; CMR Standard of the German List (Canada); ECx - Conc associated with x% respo Chemical Substances (Jap response; ERG - Emerge GLP - Good Laboratory P cer; IATA - International Construction and Equipm Half maximal inhibitory c tion; IECSC - Inventory o tional Maritime Dangerou Industrial Safety and H Standardisation; KECI - K tration to 50 % of a test (Median Lethal Dose); MA lution from Ships; MERC of Dangerous Goods; n.o. - No Observed (Adverse) fect Level; NOELR - No Norm; NTP - National Toxi icals; OECD - Organisatio fice of Chemical Safety a and Toxic substance; PIC stances; (Q)SAR - (Quant (EC) No 1907/2006 of th Registration, Evaluation, Accelerating Decompositi Chemical Substance Inve Thailand Existing Chemica States); UN - United Nat Transport of Dangerous WHMIS - Workplace Hazar
Permissible concentration - short term exposure limit ry of Industrial Chemicals
ANTT - National Agency for il
ASTM - American Society for the Testing of Materials
- Carcinogen, Mutagen or Reproductive Toxicant
DIN nstitute for Standardisation
DSL - Domestic Substances ntration associated with x% response
ELx - Loading rate se
EmS - Emergency Schedule
ENCS - Existing and New n)
ErCx - Concentration associated with x% growth rate cy Response Guide
GHS - Globally Harmonised System
actice
IARC - International Agency for Research on Canir Transport Association
IBC - International Code for the nt of Ships carrying Dangerous Chemicals in Bulk
IC50 ncentration
ICAO - International Civil Aviation Organiza- Existing Chemical Substances in China
IMDG - Interna- Goods
IMO - International Maritime Organisation
ISHL alth Law (Japan)
ISO - International Organisation for rea Existing Chemicals Inventory
LC50 - Lethal Concenopulation
LD50 - Lethal Dose to 50% of a test population POL - International Convention for the Prevention of Pol- SUR - The Agreement for the Facilitation of the Transport . - Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC ffect Concentration
NO(A)EL - No Observed (Adverse) Efbservable Effect Loading Rate
NOM - Official Mexican ology Program
NZIoC - New Zealand Inventory of Chemfor Economic Co-operation and Development
OPPTS - Ofd Pollution Prevention
PBT - Persistent, Bioaccumulative S - Philippines Inventory of Chemicals and Chemical Subtative) Structure Activity Relationship
REACH - Regulation European Parliament and of the Council concerning the uthorisation and Restriction of Chemicals
SADT - Selfn Temperature
SDS - Safety Data Sheet
TCSI - Taiwan tory
TDG - Transportation of Dangerous Goods
TECI s Inventory
TSCA - Toxic Substances Control Act (United ons
UNRTDG - United Nations Recommendations on the oods
vPvB - Very Persistent and Very Bioaccumulative
ous Materials Information System
ANTT - National Agency for il
ASTM - American Society for the Testing of Materials
- Carcinogen, Mutagen or Reproductive Toxicant
DIN nstitute for Standardisation
DSL - Domestic Substances ntration associated with x% response
ELx - Loading rate se
EmS - Emergency Schedule
ENCS - Existing and New n)
ErCx - Concentration associated with x% growth rate cy Response Guide
GHS - Globally Harmonised System
actice
IARC - International Agency for Research on Canir Transport Association
IBC - International Code for the nt of Ships carrying Dangerous Chemicals in Bulk
IC50 ncentration
ICAO - International Civil Aviation Organiza- Existing Chemical Substances in China
IMDG - Interna- Goods
IMO - International Maritime Organisation
ISHL alth Law (Japan)
ISO - International Organisation for rea Existing Chemicals Inventory
LC50 - Lethal Concenopulation
LD50 - Lethal Dose to 50% of a test population POL - International Convention for the Prevention of Pol- SUR - The Agreement for the Facilitation of the Transport . - Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC ffect Concentration
NO(A)EL - No Observed (Adverse) Efbservable Effect Loading Rate
NOM - Official Mexican ology Program
NZIoC - New Zealand Inventory of Chemfor Economic Co-operation and Development
OPPTS - Ofd Pollution Prevention
PBT - Persistent, Bioaccumulative S - Philippines Inventory of Chemicals and Chemical Subtative) Structure Activity Relationship
REACH - Regulation European Parliament and of the Council concerning the uthorisation and Restriction of Chemicals
SADT - Selfn Temperature
SDS - Safety Data Sheet
TCSI - Taiwan tory
TDG - Transportation of Dangerous Goods
TECI s Inventory
TSCA - Toxic Substances Control Act (United ons
UNRTDG - United Nations Recommendations on the oods
vPvB - Very Persistent and Very Bioaccumulative
ous Materials Information System
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.
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