11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - female - > 2.000 mg/kg (OECD Test Guideline 420)
LC50 Inhalation - Rat - male and female - 4 h - > 0,83 mg/l - dust/mist (OECD Test Guideline 403)
Remarks: (highest concentration to be prepared) (in analogy to similar products)
The value is given in analogy to the following substances: sodium dihydrogen phosphate
LD50 Dermal - Rat - male and female - > 2.000 mg/kg (OECD Test Guideline 402)
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation - 24 h
Remarks: (ECHA)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: No eye irritation - 24 h (OECD Test Guideline 405)
Respiratory or skin sensitization
Local lymph node assay (LLNA) - Mouse
Result: negative (OECD Test Guideline 429)
Germ cell mutagenicity
Test Type: Micronucleus test
Test system: Human lymphocytes
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 487
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: mouse lymphoma cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 490
Result: negative
Remarks: (ECHA)
Test Type: Ames test
Test system: Escherichia coli/Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
Lowered blood pressure, Abdominal pain, Nausea, Vomiting
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
After uptake of large quantities:
Possible symptoms:
Nausea
Vomiting gastric pain
Diarrhea
Discomfort
However, when the product is handled appropriately, hazardous effects are unlikely to occur.
Handle in accordance with good industrial hygiene and safety practice.