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Rizatriptan

Rizatriptan Structure
  • ₹0
  • Product name: Rizatriptan
  • CAS: 144034-80-0
  • MF: C15H19N5
  • MW: 269.34
  • EINECS:
  • MDL Number:MFCD03840591
  • Synonyms:n,n-dimethyl-5-(1h-1,2,4-triazol-1-ylmethyl)-1h-indole-3-ethanamine;n,n-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1h-indol-3-yl]ethanamine;RIZATRIPTAN;diMethyl({2-[5-(1H-1,2,4-triazol-1-ylMethyl)-1H-indol-3-yl]ethyl})aMine;2-(5-((1H-1,2,4-Triazol-1-yl)Methyl)-1H-indol-3-yl)-N,N-diMethylethanaMine;1H-Indole-3-ethanaMine,N,N-diMethyl-5-(1H-1,2,4-triazol-1-ylMethyl)-;Rizatriptan###144034-80-0;2-(5-((1H-1,2,4-Triazol-1-yl)
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :178-180°C
Boiling point :504.8±60.0 °C(Predicted)
Density :1.21±0.1 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
pka :16.98±0.30(Predicted)
Water Solubility :42 mg/mL
InChI :InChI=1S/C15H19N5/c1-19(2)6-5-13-8-17-15-4-3-12(7-14(13)15)9-20-11-16-10-18-20/h3-4,7-8,10-11,17H,5-6,9H2,1-2H3
InChIKey :ULFRLSNUDGIQQP-UHFFFAOYSA-N
SMILES :N1C2=C(C=C(CN3C=NC=N3)C=C2)C(CCN(C)C)=C1
CAS DataBase Reference :144034-80-0(CAS DataBase Reference)
EPA Substance Registry System :Acetonitrile, 2,2-dibromo-2-chloro- (144034-80-0)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P281 Use personal protective equipment as required.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P314 Get medical advice/attention if you feel unwell.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Rizatriptan is reported to be a very effective acute migraine drug. It is reported to display high agonist activity at mainly the serotonin 5-HT1B and 5-HT1D receptor subtypes.

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Suppliers and manufacturers

Stereokem Pvt Ltd J S LABS OCEAN TRADING CORPORATION CLEARSYNTH LABS LTD. A.J Chemicals CHEMSWORTH SynZeal Research Pvt Ltd Pharmaffiliates Analytics and Synthetics P. Ltd Vishal Health Specialities A R Life Sciences Private Limited