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ChemicalBook >> CAS DataBase List >> 3-Chloro-N-{(1S)-2-[(N,N-dimethylglycyl)amino]-1-[(4-{8-[(1S)-1-hydroxyethyl]imidazo[1,2-a]pyridin-2-yl}phenyl)methyl]ethyl}-4-[(1-methylethyl)oxy]benzamide

3-Chloro-N-{(1S)-2-[(N,N-dimethylglycyl)amino]-1-[(4-{8-[(1S)-1-hydroxyethyl]imidazo[1,2-a]pyridin-2-yl}phenyl)methyl]ethyl}-4-[(1-methylethyl)oxy]benzamide

3-Chloro-N-{(1S)-2-[(N,N-dimethylglycyl)amino]-1-[(4-{8-[(1S)-1-hydroxyethyl]imidazo[1,2-a]pyridin-2-yl}phenyl)methyl]ethyl}-4-[(1-methylethyl)oxy]benzamide price.
  • $33 - $5720
  • Product name: 3-Chloro-N-{(1S)-2-[(N,N-dimethylglycyl)amino]-1-[(4-{8-[(1S)-1-hydroxyethyl]imidazo[1,2-a]pyridin-2-yl}phenyl)methyl]ethyl}-4-[(1-methylethyl)oxy]benzamide
  • CAS: 1088965-37-0
  • MF: C32H38ClN5O4
  • MW: 592.13
  • EINECS:256-495-9
  • MDL Number:MFCD16038931
  • Synonyms:GSK-923295;3-Chloro-N-((S)-1-(2-(dimethylamino)acetamido)-3-(4-(8-((S)-1-hydroxyethyl)-imidazo[1,2-a]pyri;3-chloro-N-((S)-1-(2-(diMethylaMiNA)acetaMido)-3-(4-(8-((R)-1-hydroxyethyl)iMidazo[1,2-a]pyridin-2-yl)phenyl)propan-2-yl)-4-isopropoxybenzaMide;3-Chloro-N-((S)-1-(2-(dimethylamino)acetamido)-3-(4-(8-((S)-1-hydroxyethyl)-imidazo[1,2-a]pyridin;Benzamide, 3-chloro-N-[(1S)-2-[[2-(dimethylamino)acetyl]amino]-1-[[4-[8-[(1S)-1-hydroxyethyl]imidazo[1,2-a]pyridin-2-yl]phenyl]methyl]ethyl]-4-(1-methylethoxy)-;3-Chloro-N-{(1S)-2-[(N,N-dimethylglycyl)amino]-1-[(4-{8-[(1S)-1-hydroxyethyl]imidazo[1,2-a]pyridin-2-yl}phenyl)methyl]ethyl}-4-[(1-methylethyl)oxy]benzamide GSK-923295;3-Chloro-N-{(1S)-2-[(N,N-dimethylglycyl)amino]-1-[(4-{8-[(1S)-1-hydroxyethyl]imidazo[1,2-a]pyridin-2-yl}phenyl)methyl]ethyl}-4-[(1-methylethyl)oxy]benzamide;CENP-E inhibitor GS923295
23 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TRC
  • Usbiological
Package
  • 1mg
  • 5MG
  • 10mg
  • 50mg
  • 100mg
  • 1g
  • 10mM(in 1mL DMSO)
  • 250mg
  • ManufacturerAK Scientific
  • Product number1762AA
  • Product description3-Chloro-N-((S)-1-(2-(dimethylamino)acetamido)-3-(4-(8-((S)-1-hydroxyethyl)imidazo[1,2-a]pyridin-2-yl)phenyl)propan-2-yl)-4-isopropoxybenzamide
  • Packaging1g
  • Price$5720
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008144
  • Product descriptionGSK-923295 95.00%
  • Packaging5MG
  • Price$352
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3450
  • Product descriptionGSK-923295
  • Packaging10mM(in 1mL DMSO)
  • Price$210
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFG45994
  • Product descriptionGSK 923295
  • Packaging50mg
  • Price$787.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18389
  • Product descriptionGSK923295 ≥98%
  • Packaging1mg
  • Price$33
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18389
  • Product descriptionGSK923295 ≥98%
  • Packaging5mg
  • Price$148
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18389
  • Product descriptionGSK923295 ≥98%
  • Packaging10mg
  • Price$262
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18389
  • Product descriptionGSK923295 ≥98%
  • Packaging50mg
  • Price$814
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM151203
  • Product description3-Chloro-N-((S)-1-(2-(dimethylamino)acetamido)-3-(4-(8-((S)-1-hydroxyethyl)-imidazo[1,2-a]pyridin-2-yl)phenyl)propan-2-yl)-4-isopropoxybenzamide 98%
  • Packaging100mg
  • Price$987
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0056
  • Product descriptionGSK-923295 99.56%
  • Packaging5mg
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0056
  • Product descriptionGSK-923295 99.56%
  • Packaging10mg
  • Price$216
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0056
  • Product descriptionGSK-923295 99.56%
  • Packaging50mg
  • Price$756
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0056
  • Product descriptionGSK-923295 99.56%
  • Packaging100mg
  • Price$1320
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004618
  • Product descriptionGSK-923295 98+%
  • Packaging50mg
  • Price$697
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004618
  • Product descriptionGSK-923295 98+%
  • Packaging100mg
  • Price$1128
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7812
  • Product descriptionGSK923295 >98%
  • Packaging100mg
  • Price$625
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1762AA 3-Chloro-N-((S)-1-(2-(dimethylamino)acetamido)-3-(4-(8-((S)-1-hydroxyethyl)imidazo[1,2-a]pyridin-2-yl)phenyl)propan-2-yl)-4-isopropoxybenzamide 1g $5720 2021-12-16 Buy
American Custom Chemicals Corporation API0008144 GSK-923295 95.00% 5MG $352 2021-12-16 Buy
ApexBio Technology A3450 GSK-923295 10mM(in 1mL DMSO) $210 2021-12-16 Buy
Biosynth Carbosynth FG45994 GSK 923295 50mg $787.5 2021-12-16 Buy
Cayman Chemical 18389 GSK923295 ≥98% 1mg $33 2024-03-01 Buy
Cayman Chemical 18389 GSK923295 ≥98% 5mg $148 2024-03-01 Buy
Cayman Chemical 18389 GSK923295 ≥98% 10mg $262 2024-03-01 Buy
Cayman Chemical 18389 GSK923295 ≥98% 50mg $814 2024-03-01 Buy
Chemenu CM151203 3-Chloro-N-((S)-1-(2-(dimethylamino)acetamido)-3-(4-(8-((S)-1-hydroxyethyl)-imidazo[1,2-a]pyridin-2-yl)phenyl)propan-2-yl)-4-isopropoxybenzamide 98% 100mg $987 2021-12-16 Buy
ChemScene CS-0056 GSK-923295 99.56% 5mg $132 2021-12-16 Buy
ChemScene CS-0056 GSK-923295 99.56% 10mg $216 2021-12-16 Buy
ChemScene CS-0056 GSK-923295 99.56% 50mg $756 2021-12-16 Buy
ChemScene CS-0056 GSK-923295 99.56% 100mg $1320 2021-12-16 Buy
Crysdot CD31004618 GSK-923295 98+% 50mg $697 2021-12-16 Buy
Crysdot CD31004618 GSK-923295 98+% 100mg $1128 2021-12-16 Buy
DC Chemicals DC7812 GSK923295 >98% 100mg $625 2021-12-16 Buy

Properties

Melting point :197-198℃
Density :1.25
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Sonicated)
pka :13.12±0.20(Predicted)
form :Solid
color :Pale Yellow to Light Yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

GSK 923295 is the first potent, CENP-E-selective inhibitor that has been tested in Phase I clinical trials for treatment of Refractory Cancers.

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