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ChemicalBook >> CAS DataBase List >> 4-HYDROXY-1-METHYL-2-QUINOLONE


  • $60 - $131
  • Product name: 4-HYDROXY-1-METHYL-2-QUINOLONE
  • CAS: 1677-46-9
  • MF: C10H9NO2
  • MW: 175.18
  • EINECS:216-830-3
  • MDL Number:MFCD00024052
  • Synonyms:AURORA KA-2363;4-HYDROXY-1-METHYL-2-QUINOLONE;4-HYDROXY-1-METHYL-1,2-DIHYDROQUINOLIN-2-ONE;4-HYDROXY-1-METHYL-1H-QUINOLIN-2-ONE;4-HYDROXY-1-METHYL-2(1H)-QUINOLONE;4-HYDROXY-N-METHYL-2-QUINOLONE;1-methyl-4-hydroxy-2-chinolinon ;1-methyl-4-hydroxy-2-chinolon
3 prices
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  • Sigma-Aldrich
  • TCI Chemical


  • 5g
  • 25g
  • ManufacturerSigma-Aldrich
  • Product number168696
  • Product description4-Hydroxy-1-methyl-2(1H)-quinolone 98%
  • Packaging5g
  • Price$61.3
  • Updated2018-11-13
  • Buy
  • ManufacturerTCI Chemical
  • Product numberM1009
  • Product description4-Hydroxy-1-methyl-2-quinolone >98.0%(HPLC)(T)
  • Packaging25g
  • Price$131
  • Updated2018-11-22
  • Buy
  • ManufacturerTCI Chemical
  • Product numberM1009
  • Product description4-Hydroxy-1-methyl-2-quinolone >98.0%(HPLC)(T)
  • Packaging5g
  • Price$60
  • Updated2018-11-22
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich 168696 4-Hydroxy-1-methyl-2(1H)-quinolone 98% 5g $61.3 2018-11-13 Buy
TCI Chemical M1009 4-Hydroxy-1-methyl-2-quinolone >98.0%(HPLC)(T) 25g $131 2018-11-22 Buy
TCI Chemical M1009 4-Hydroxy-1-methyl-2-quinolone >98.0%(HPLC)(T) 5g $60 2018-11-22 Buy


Melting point: :269-271 °C(lit.)
Boiling point: :306.47°C (rough estimate)
Density  :1.326
refractive index  :1.5060 (estimate)
CAS DataBase Reference :1677-46-9(CAS DataBase Reference)

Safety Information

Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.


4-Hydroxy-1-methyl-2(1H)-quinolone was used as nucleophile in electrochemical oxidation of catechols and the reaction was studied by cyclic voltammetry and controlled-potential coulometry. It was used in ceric ammonium nitrate-mediated oxidative cycloaddition of 1,3-dicarbonyls to conjugated compounds to yield substituted dihydrofurans, dihydrofurocoumarins, dihydrofuroquinolinones and dihydrofurophenalenones. It was used in the synthesis of :3-(4-methoxybenzyl)-4-hydroxy-1-methylquinolinone3-(benzo[d][1,3]dioxol-5-ylmethyl)-4-hydroxy-1-methylquinolin-2(1H)-one3-(4-chlorobenzyl)-4-hydroxy-1-methylquinolin-2(1H)-one3,3′-bis(4-chlorobenzylidene)-1,10-methylquinolin-2,20-(1H)-one

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