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ChemicalBook >> CAS DataBase List >> AC-DEVD-AFC

AC-DEVD-AFC

AC-DEVD-AFC price.
  • $40 - $285
  • Product name: AC-DEVD-AFC
  • CAS: 201608-14-2
  • MF: C30H34F3N5O13
  • MW: 729.61
  • EINECS:
  • MDL Number:MFCD01310970
  • Synonyms:N-ACETYL-ASP-GLU-VAL-ASP 7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN;N-ACETYL-ASP-GLU-VAL-ASP-(7-AMINO-4-TRIFLUOROMETHYLCOUMARIN);N-ACETYL-ASP-GLU-VAL-ASP-7-AMINO-4-TRIFLUOROMETHYLCOUMARIN AFC;CASPASE 3 (APOPAIN) SUBSTRATE 1F, FLUOROGENIC;CASPASE-3 SUBSTRATE (AFC);CASPASE-3 SUBSTRATE VII, FLUOROGENIC;CASPASE-3 FLUOROGENIC SUBSTRATE;FLUOROGENIC CASPASE 3 SUBSTRATE AC-DEVD-AFC
5 prices
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Brand

  • Alfa Aesar
  • Cayman Chemical
  • Sigma-Aldrich

Package

  • 1mg
  • 5mg
  • 10mg
  • ManufacturerAlfa Aesar
  • Product numberJ64134
  • Product descriptionN-Acetyl-Asp-Glu-Val-Asp-7-amino-4-(trifluoromethyl)coumarin
  • Packaging5mg
  • Price$285
  • Updated2021-03-22
  • Buy
  • ManufacturerCayman Chemical
  • Product number14459
  • Product descriptionAc-DEVD-AFC ≥98%
  • Packaging10mg
  • Price$280
  • Updated2021-03-22
  • Buy
  • ManufacturerCayman Chemical
  • Product number14459
  • Product descriptionAc-DEVD-AFC ≥98%
  • Packaging1mg
  • Price$40
  • Updated2021-03-22
  • Buy
  • ManufacturerCayman Chemical
  • Product number14459
  • Product descriptionAc-DEVD-AFC ≥98%
  • Packaging5mg
  • Price$150
  • Updated2021-03-22
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberA0466
  • Product descriptionN-Acetyl-Asp-Glu-Val-Asp-7-amido-4-trifluoromethylcoumarin ≥90% (HPLC), powder
  • Packaging1mg
  • Price$164
  • Updated2021-03-22
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alfa Aesar J64134 N-Acetyl-Asp-Glu-Val-Asp-7-amino-4-(trifluoromethyl)coumarin 5mg $285 2021-03-22 Buy
Cayman Chemical 14459 Ac-DEVD-AFC ≥98% 10mg $280 2021-03-22 Buy
Cayman Chemical 14459 Ac-DEVD-AFC ≥98% 1mg $40 2021-03-22 Buy
Cayman Chemical 14459 Ac-DEVD-AFC ≥98% 5mg $150 2021-03-22 Buy
Sigma-Aldrich A0466 N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-trifluoromethylcoumarin ≥90% (HPLC), powder 1mg $164 2021-03-22 Buy

Properties

Boiling point: :1152.7±65.0 °C(Predicted)
Density  :1.495±0.06 g/cm3(Predicted)
storage temp.  :-20°C
solubility  :H2O: 1 mg/mL
form  :powder
pka :4.09±0.10(Predicted)
color  :white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

During apoptosis, activated caspase-3 cleaves several substrates, including poly(ADP-ribose) polymerase, which it specifically targets at the amino sequence DEVD. Ac-DEVD-AFC is a fluorogenic substrate for activated caspase-3 (Km = 9.7 μM), as well as related caspases. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.

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