醋酸去氢表雄酮
| 中文名称 | 醋酸去氢表雄酮 |
|---|---|
| 中文同义词 | 醋酸去氢表雄酮,去氢表雄酮醋酸酯;3-乙酸脱氢异雄甾酮;3-乙酸脱氢异雄(甾)酮;反式-醋酸脱氢雄(甾)酮;醋酸去氢表雄酮(甾体);醋酸去氢表雄酮 英文名称;醋酸去氢素雄酮;3-醋酸去氢表雄酮 |
| 英文名称 | Dehydroepiandrosterone acetate |
| 英文同义词 | 3B-ACETOXY-5-ANDROSTEN-17-ONE;3BETA-ACETOXY-5-ANDROSTEN-17-ONE;3BETA-ACETOXY-5-ANDROSTEN-17-ONE ACETATE;3B-HYDROXYANDROST-5-EN-17-ONEACETATE;3-(ACETYLOXY)ANDROST-5-ENE-17-ONE;5-ANDROSTEN-3-BETA-ACETOXY-3-ONE;5-ANDROSTEN-3BETA-OL-17-ONE 3-ACETATE;5-ANDROSTEN-3-BETA-OL-17-ONE ACETATE |
| CAS号 | 853-23-6 |
| 分子式 | C21H30O3 |
| 分子量 | 330.47 |
| EINECS号 | 212-714-1 |
| 相关类别 | 手性砌块;小分子抑制剂，天然产物;小分子抑制剂;医药原料;中间体;维生素与氨基酸;原料;激素甾体;医药中间体;不对称合成;其他化学试剂;化合物;甾体激素原料中间体;合成材料;原料药;医用原料;男性保健原料;药物杂质及中间体;医药原料和中间体;化工中间体;原料药;有机化工原料;工业化;对照品;Pharmaceutical Intermediates;Steroids;17-Ketosteroids;Biochemistry;Hydroxyketosteroids;Chemistry;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;API;Inhibitors |
| Mol文件 | 853-23-6.mol |
| 结构式 |  |
醋酸去氢表雄酮 性质
| 熔点 | 168-170 °C(lit.) |
|---|---|
| 沸点 | 407.89°C (rough estimate) |
| 密度 | 1.0998 (rough estimate) |
| 蒸气压 | 0Pa at 20℃ |
| 折射率 | 1.5192 (estimate) |
| 储存条件 | Refrigerator |
| 溶解度 | 可溶于氯仿、DMSO（微溶）、甲醇（微溶） |
| 形态 | 固体 |
| 颜色 | 白色至类白色 |
| 旋光性 (optical activity) | [α]20/D +2.4°, c = 2 in ethanol |
| 水溶解性 | 11.5mg/L(temperature not stated) |
| InChI | InChI=1/C21H30O3/c1-13(22)24-15-8-10-20(2)14(12-15)4-5-16-17-6-7-19(23)21(17,3)11-9-18(16)20/h4,15-18H,5-12H2,1-3H3/t15-,16-,17-,18-,20-,21-/s3 |
| InChIKey | NCMZQTLCXHGLOK-KJBVPOJVSA-N |
| SMILES | C[C@]12CC[C@H](OC(=O)C)CC1=CC[C@@]1([H])[C@]3([H])CCC(=O)[C@@]3(C)CC[C@]21[H] |&1:1,4,13,15,21,25,r| |
| LogP | 5.1 at 20℃ |
| CAS 数据库 | 853-23-6 |
Dehydroisoandrosterone implants increases aggression in a laboratory-based simulated territorial intrusion. Brains of Dehydroisoandrosterone-implanted birds show higher aromatase mRNA expression in the preoptic area (POA) and higher androgen receptor mRNA expression in the periventricular nucleus of the medial striatum (pvMSt) and ventromedial nucleus of the hypothalamus (VMH). The Dehydroisoandrosterone-induced increases in aromatase expression in the POA and androgen receptor expression in the pvMSt are consistent with previously reported seasonal increases in these markers associated with naturally elevated Dehydroisoandrosterone levels. Dehydroisoandrosterone supplementation (10.2 mg/kg) alone significantly increases mice body weight (BW), muscle weight, testosterone level, and glycogen contents (liver and muscle) when compared with SC group.
安全信息
| 安全说明 | 22-24/25 |
|---|---|
| WGK Germany | 3 |
| RTECS号 | BV8396810 |
| 提供商 | 语言 |
|---|---|
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英文
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