3,4'-二羟基黄酮
| 中文名称 | 3,4'-二羟基黄酮 |
|---|---|
| 中文同义词 | |
| 英文名称 | 3,4'-DIHYDROXYFLAVONE |
| 英文同义词 | 4'-HYDROXYFLAVONOL;4',3-DIHYDROXYFLAVONE;3,4'-DIHYDROXYFLAVONE;4H-1-Benzopyran-4-one, 3-hydroxy-2-(4-hydroxyphenyl)-;3-Hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one;3,4'-Dihydroxyflavone>3-Hydroxy-2-(4-hydroxyphenyl)chromone;Influenza Virus,3,4'-Dihydroxyflavone,3,4'Dihydroxyflavone,inhibit,Inhibitor,3,4' Dihydroxyflavone,3,4'-DHF |
| CAS号 | 14919-49-4 |
| 分子式 | C15H10O4 |
| 分子量 | 254.24 |
| EINECS号 | |
| 相关类别 | 吡喃;Di-substituted Flavones |
| Mol文件 | 14919-49-4.mol |
| 结构式 |  |
3,4'-二羟基黄酮 性质
| 熔点 | 275-276°C |
|---|---|
| 沸点 | 452.5±45.0 °C(Predicted) |
| 密度 | 1.472±0.06 g/cm3(Predicted) |
| 储存条件 | Keep in dark place,Sealed in dry,Room Temperature |
| 溶解度 | DMSO：≥ 155 mg/mL (609.66 mM)；水：< 0.1 mg/mL（不溶） |
| 形态 | 粉末晶体 |
| 酸度系数(pKa) | 8.94±0.20(Predicted) |
| 颜色 | 白色至琥珀色至深绿色 |
| CAS 数据库 | 14919-49-4 |
3,4'-Dihydroxyflavone (3,4'-DHF) 是一种具有口服活性的黄酮类化合物，具有抗病毒活性，如，甲型流感病毒 (Influenza A virus)。
3,4'-Dihydroxyflavone (3,4'-DHF; PO, 1 mg/kg per 30 μL, daily, 5 days) significantly decreases virus titers and pathological changes in the lung and reduced body weight loss and death.
| Animal Model: | 3,4'-Dihydroxyflavone (3,4'-DHF; PO, 1 mg/kg per 30 μL, daily, 5 days) significantly decreases virus titers and pathological changes in the lung and reduced body weight loss and death. |
| Dosage: | 1 mg/kg per 30 μL. |
| Administration: | Oral administration daily for 5 days. |
| Result: | Significantly decreased virus titers and pathological changes in the lung and reduced body weight loss and death. |
安全信息
| 海关编码 | 2932.99.7000 |
|---|
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/01/25 | HY-111802 | 3,4'-二羟基黄酮 3,4'-Dihydroxyflavone | 14919-49-4 | 100mg | 950元 |
| 2024/01/25 | HY-111802 | 3,4'-二羟基黄酮 3,4'-Dihydroxyflavone | 14919-49-4 | 10mM * 1mLin DMSO | 1045元 |