尿苷-5'-二磷酸钠盐
| 中文名称 | 尿苷-5'-二磷酸钠盐 |
|---|---|
| 中文同义词 | 尿苷-5'-二磷酸钠盐;5-尿苷二磷酸钠盐;5- UDP 尿苷-5-二磷酸;尿苷-5-二磷酸酯钠盐(UDP钠盐、尿苷-5-二磷酸钠盐、5-二磷酸尿苷钠盐、二磷酸尿苷二钠);5-尿苷二磷酸/尿苷-5′-二磷酸;5-尿苷二磷酸;5-尿苷磷酸钠盐;UDP钠盐 |
| 英文名称 | URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT |
| 英文同义词 | Uridine 5′-diphosphate sodium salt from;UDP 2NA;URIDINE 5'-DIPHOSPHATE DISODIUM SALT;URIDINE 5'-DIPHOSPHORIC ACID DISODIUM SALT;Uridine-5' diphosphate(UDP)disodium salt;Uridine 5′-(trihydrogen diphosphate) sodium salt from Saccharomyces cerevisiae,UDP sodium salt, Uridine 5′-(trihydrogen pyrophosphate) sodium salt;uridine 5'-diphosphate sodium from*yeast;URIDINE-5'-DIPHOSPHATE, SODIUM SALT 98+% |
| CAS号 | 21931-53-3 |
| 分子式 | C9H12N2Na2O12P2 |
| 分子量 | 448.12 |
| EINECS号 | 999-999-2 |
| 相关类别 | 其他生化试剂;核苷，核苷酸，寡核苷酸;生化试剂;核苷酸类;植物激素及核酸类;生化试剂-植物激素及核酸类;通用生化试剂-核酸;Bases & Related Reagents;Carbohydrates & Derivatives;Heterocycles;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals |
| Mol文件 | 21931-53-3.mol |
| 结构式 |  |
尿苷-5'-二磷酸钠盐 性质
| 储存条件 | -20°C |
|---|---|
| 溶解度 | 在水中的溶解度为100mg/mL，透明，无色至微黄色 |
| 形态 | 粉末 |
| 颜色 | 白色 |
| 水溶解性 | Soluble in water to 100mM |
| 稳定性 | 吸湿性 |
|
Human Endogenous Metabolite
|
Uridine 5'-diphosphate sodium salt (100 μM; for 15 min) significantly induces microglial CCL2 and CCL3 mRNA expression.
Uridine 5'-diphosphate sodium salt (100 μM; 3 hours) induces chemokine expression in microglia.
Uridine 5'-diphosphate sodium salt (100 μM; 0.5, 1, 3, 6 12 hours) induces expression of mRNA encoding CCL2 and CCL3 within 30 min, and such expression reaches maximal levels at 1 h, returning to basal levels at 3-12 h.
UDP (10, 100, 1000 μM; 3 hours) induces a concentration-dependent increase in the expression of chemokines at both the mRNA and protein level.
Uridine 5'-diphosphate sodium salt (100 μM; for 15 min) induces activation of NFATc1 and NFATc2 in microglia.
RT-PCR
| Cell Line: | Primary microglia |
| Concentration: | 100 μM |
| Incubation Time: | For 15 min |
| Result: | Significantly induced microglial CCL2 and CCL3 mRNA expression. |
安全信息
| 危险品标志 | Xn |
|---|---|
| 危险类别码 | 22-68/22-68/20/21/22-20/21/22 |
| 安全说明 | 36/37 |
| WGK Germany | 3 |
| 海关编码 | 29349990 |
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/01/25 | HY-W010832 | 尿苷-5'-二磷酸钠盐 Uridine-5'-diphosphate disodium salt | 21931-53-3 | 100mg | 500元 |
| 2024/01/25 | HY-W010832 | 尿苷-5'-二磷酸钠盐 Uridine-5'-diphosphate disodium salt | 21931-53-3 | 10mM * 1mLin Water | 550元 |