D-蛋氨酸
| 中文名称 | D-蛋氨酸 |
|---|---|
| 中文同义词 | D-2-氨基-4-甲硫基丁酸;D-蛋氨酸;D-甲硫氨酸(D-蛋氨酸);D-甲硫氨酸/D-蛋氨酸/D-2-氨基-4-甲硫基丁酸/D-甲硫基丁氨酸;D-METHIONINE D-蛋氨酸;D-甲硫氨酸,D-2-氨基-4-甲硫基丁酸;D-蛋氨酸,99%;D-蛋氨酸/D-甲硫氨酸 |
| 英文名称 | D-Methionine |
| 英文同义词 | D-2-AMINO-4-[METHYLTHIO]BUTANOIC ACID;d-2-amino-4-(methylthio)butyric acid;D-LOBAMINE;D-METHIONINE;D-BANTHIONINE;(R)-2-AMINO-4-(METHYLMERCAPTO)BUTYRIC ACID;(2R)-2-Amino-4-methylsulfanylbutanoic acid;D-Methionine (H-D-Met-OH) |
| CAS号 | 348-67-4 |
| 分子式 | C5H11NO2S |
| 分子量 | 149.21 |
| EINECS号 | 206-483-6 |
| 相关类别 | D系列氨基酸;氨基酸及其衍生物;生化试剂;精细化学品;氨基酸;其他生化试剂;保护氨基酸;氨基酸和衍生物;氨基酸类;保护氨基酸及多肽类产品;化学生物学;标准品;非天然氨基酸;医药原料;氨基酸 Amino Acid;天然氨基酸极其衍生物;氨基酸衍生物;营养增补剂;化学试剂;中药对照品;对照品;Amino ACIDS SERIES;Amino Acid Derivatives;PROTECTED AMINO ACID & PEPTIDES;Methionine [Met, M];Amino Acids and Derivatives;Amino Acids and Derivatives;Amino Acids;生化试剂-氨基酸类;原料药API;原料;生化试剂-氨基酸;D-氨基酸;有机化工原料;有机中间体;化工原料;通用生化试剂-氨基酸;对照品 |
| Mol文件 | 348-67-4.mol |
| 结构式 |  |
D-蛋氨酸 性质
| 熔点 | 273-275 °C |
|---|---|
| 比旋光度 | -24 º (c=8, 6N HCl) |
| 沸点 | 306.9±37.0 °C(Predicted) |
| 密度 | 1.113 (estimate) |
| 折射率 | 1.5216 (estimate) |
| 储存条件 | Sealed in dry,Room Temperature |
| 溶解度 | 53g/l（20°C） |
| 酸度系数(pKa) | 2.23±0.10(Predicted) |
| 形态 | 粉末 |
| 颜色 | 白色至类白色 |
| 水溶解性 | 53 g/L (20 ºC) |
| Merck | 14,5975 |
| BRN | 1722293 |
| 稳定性 | 稳定的。与强氧化剂不相容。 |
| LogP | 0.370 (est) |
| CAS 数据库 | 348-67-4(CAS DataBase Reference) |
| NIST化学物质信息 | D-(l)-Methionine(348-67-4) |
| EPA化学物质信息 | D-Methionine (348-67-4) |
GABA A receptor
The incubation of human plasma with Methionine (D-methionine) and CP leads to the formation of a Pt-D-methionine complex independent of the order of addition. In plasma, an early CP hydrolysis product reacts with Methionine to form a 1:1 complex that is followed by the formation of a 2:1 compound at a later time point. The formation of these Pt-D-methionine species plays an important role in the processes by which Methionine protects mammalian organisms against CP-induced toxicities.
When Methionine (D-methionine) is administered along with cisplatin the cell density is 0.8±0.070 (SEM), significantly larger than in rats treated with only cisplatin (P<0.01) while not significantly different from controls or from animals treated only with D-methionine (P>0.05). When Methionine is administered alone the average cell density is 0.95±0.099 (SEM) and not significantly different from controls (P>0.05).
安全信息
| 危险品标志 | Xi |
|---|---|
| 危险类别码 | 33-36/37/38 |
| 安全说明 | 22-24/25-36-26 |
| WGK Germany | 3 |
| RTECS号 | PD0455000 |
| TSCA | Yes |
| 海关编码 | 29304090 |
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