氯胺-T 三水合物

氯胺-T 三水合物

中文名称氯胺-T 三水合物
中文同义词三水合氯铵-T;氯铵-T三水;氯胺T钠;氯胺T,三水;氯胺T三水合物;亚明T;氯亚明T三水合物,氯胺T三水合物,三水合氯铵-T,对甲苯磺酰氯胺钠三水合物;氯铵-T三水(>98%,BR)
英文名称Chloramine-T trihydrate
英文同义词CHLORAMINE T 3-HYDRATE;Chloramine-T trihydrate, ACS, 98.0-103.0%;Benzenesulfonamide, N-chloro-4-methyl-, sodium salt, trihydrate;chloramine-t trihydrate, acs;CHLORAMINE T REAGENT (ACS);N-Chloro-p-toluenesulfonamide sodium salt, Chloraminum;Chloramine-T trihydrate,97+%;SODIUM P-TOLUENESULFONCH
CAS号7080-50-4
分子式C7H11ClNNaO3S
分子量247.67
EINECS号615-172-8
相关类别氧化;有机化学;卤代物;其他生化试剂;通用试剂;合成试剂;Chlorination;Classes of Metal Compounds;Halogenation;Na (Sodium) Compounds (excluding simple sodium salts);Oxidation;Synthetic Organic Chemistry;生化试剂;消毒剂;有机化工原料;消杀;化工原料;基础有机试剂;Typical Metal Compounds;7080-50-4
Mol文件7080-50-4.mol
结构式氯胺-T 三水合物 结构式

氯胺-T 三水合物 性质

熔点167-170 °C(lit.)
密度1.43
闪点92 °C
储存条件Store at +2°C to +8°C.
溶解度可溶于H2O
形态结晶粉末
酸度系数(pKa)pK1:4.54(+1) (25°C)
颜色白色至类白色
PH值8-10 (50g/l, H2O, 20℃)
气味 (Odor)氯类气味
酸碱指示剂变色ph值范围8 - 10
水溶解性Soluble in water and ethyl alcohol. Insoluble in benzene and ethers.
敏感性Moisture Sensitive
Merck14,2075
BRN3924168
LogP2.111 (est)
CAS 数据库7080-50-4(CAS DataBase Reference)

氯胺-T 三水合物 用途与合成方法

Tosylchloramide sodium trihydrate (Chloramine T sodium trihydrate) 是广泛厨房,实验室和医院的消毒剂。也用作空气清新剂和除臭剂中的杀生物剂。

Gram-positive growth is reduced by 95% to 100% after tosylchloramide treatment, regardless of dose, with or without serum. E coli (gram-negative; with/without serum) is reduced 94% to 100% at antiseptic concentrations of 300 and 400 ppm. At 200 ppm, E coli growth is fully inhibited without serum present and by 50% with serum. At 100 and 200 ppm, cell viability remains greater than 90% under all experimental conditions. A 300-ppm, 3-minute exposure to tosylchloramide results in cell viability of up to 70%, with longer exposures producing lower viabilities. Serum does not affect cell viability in any condition.

A dose-dependently significant DNA damage in the rat tissues and inflammation is histopathologically noted around the terminal airways of the lung in both male and female rats. The 24-h exposure to 50 mg/L of chloramine-T is toxic for crayfish and leads to substantial loss of energy that became apparent during subsequently conducted physical stress. Tosylchloramide may potentiate the toxicity of many xenobiotics via metabolic activation and/or accumulation of reactive metabolites. The activities of CYP2E1, CYP1A1/2 CYP2B1/2, CYP3A4 and CYP4A1/2 enzymes significantly increase after treatment with 2.50, 5 and 10 mg/kg bw/day tosylchloramide, in a dose-dependent manner. This effect is not observed after tosylchloramide treatment at dose of 1.25 mg/kg bw/day.

用途 
容量分析中用作碘及次氯酸盐标准溶液的代用品,检定溴酸盐和卤素,测定碘化物、铊和锡、用作供给氯的试剂,消毒剂,医药(防腐剂)。

安全信息

危险品标志C
危险类别码22-31-34-42
安全说明22-26-36/37/39-45-7
危险品运输编号UN 3263 8/PG 3
WGK Germany2
RTECS号XT5616800
TSCAYes
危险等级8
包装类别III
海关编码29350090
毒性LD50 orally in Rabbit: 935 mg/kg

MSDS信息

提供商 语言
英文
中文
英文
更新日期产品编号产品名称CAS号包装价格
2024/01/25HY-U00087Tosylchloramide sodium trihydrate5 g100元
2024/01/25HY-U00087Tosylchloramide sodium trihydrate10 mM * 1 mLin DMSO110元

氯胺-T 三水合物 上下游产品信息

"氯胺-T 三水合物"相关产品信息
左氧氟沙星半水合物 对甲基苯磺酰甲基异腈 氯化钠 醋酸钠 对硝基苯磺酰氯 对甲苯磺酰氯 氢氧化钠 苯磺酰氯 葡萄糖酸钠 二甲苯磺酸钠 碳酸钠 碳酸氢钠 对甲苯磺酰胺 磺酰氯 对甲苯磺酸水合物 苯甲酸钠 对甲氧基苯磺酰氯 氯胺T
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