甲氧咪草烟
中文名称 | 甲氧咪草烟 |
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中文同义词 | 甲氧咪草烟;2-(4-异丙基-4-甲基-5-氧-2-咪唑啉-2-基)-5-甲氧基甲基烟酸;(RS)-2-(4-异丙基-4-甲基-5-氧-2-咪唑啉-2-基)-5-甲氧基甲基尼古丁酸;(RS)-2-(4-异丙基-4-甲基-5-氧代-2-咪唑啉-2-基)-5-甲氧甲基吡啶-3-羧酸;金豆;甲氧咪草烟溶液, 100PM;甲氧咪草酸;乙腈中甲氧咪草烟 |
英文名称 | Imazamox |
英文同义词 | 2-(4-Isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)-5-methoxymethylnicotinic acid;IMAZAMOX;(RS)-2-(4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)-5-methoxymethylnicotinic acid;Odyseey;Raptor;Sweeper;Imazamox PESTANAL;AC299263 |
CAS号 | 114311-32-9 |
分子式 | C15H19N3O4 |
分子量 | 305.33 |
EINECS号 | |
相关类别 | 除草剂;农药;有机杂环类除草剂;除草剂原药 |
Mol文件 | 114311-32-9.mol |
结构式 |
甲氧咪草烟 性质
熔点 | 166-167°C |
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密度 | 1.39 g/cm3 |
储存条件 | 0-6°C |
溶解度 | 二甲基亚砜:20 mg/ml(65.50 mM) |
酸度系数(pKa) | pK1 2.3; pK2 3.3(at 25℃) |
InChI | InChI=1S/C15H19N3O4/c1-8(2)15(3)14(21)17-12(18-15)11-10(13(19)20)5-9(6-16-11)7-22-4/h5-6,8H,7H2,1-4H3,(H,19,20)(H,17,18,21) |
InChIKey | NUPJIGQFXCQJBK-UHFFFAOYSA-N |
SMILES | C1(C2NC(=O)C(C)(C(C)C)N=2)=NC=C(COC)C=C1C(O)=O |
CAS 数据库 | 114311-32-9(CAS DataBase Reference) |
EPA化学物质信息 | Imazamox (114311-32-9) |
Half-life of Imazamox in the soil ranges from 1 to 3 months exhibit low mammalian toxicity. Plants are treated with Imazamox (250 μM) in the nutrient solution and harvested 7 days after. Imazamox is mainly accumulated in V. sativa , six fold higher than those detected in P.vulgaris .
Imazamox (12-36 mg/kg; intraperitoneal injection; for 24-72 hours; male Sprague-Dawley rats) treatment induces toxic effects in the liver and pancreas of Sprague Dawley rats. Necrotic and degenerative changes are detected in hepatocytes at the two highest doses. Imazamox treatment reduces the size of the β-islet cells, and also induces an elevation in serum glucose and calcium.
Animal Model: | 50 male Sprague-Dawley rats (300 ± 10 g) |
Dosage: | 12 mg/kg, 24 mg/kg and 36 mg/kg |
Administration: | Intraperitoneal injection; for 24 hours, 48 hours or 72 hours |
Result: | Induced toxic effects in the liver and pancreas. |
以丙醛为起始原料,与甲醛缩合、闭环、卤化、甲氧基化等一系列反应制得甲氧咪草烟。
制备方法二
以甲氧基丙醛、草酸二乙酯、甲基异丙基酮为起始原料,经过下述一系列反应制得甲氧咪草烟。
安全信息
危险品标志 | N |
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危险类别码 | 50/53 |
安全说明 | 60-61 |
危险品运输编号 | UN3077 9/PG 3 |
WGK Germany | 3 |
毒害物质数据 | 114311-32-9(Hazardous Substances Data) |
毒性 | LD50 (technical grade) orally in rats: >5000 mg/kg; dermally in rabbits: >4000 mg/kg; LC50 by inhalation in rats: >6.3 mg/l (Glover) |
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024/01/25 | HY-100427 | Imazamox | 5 mg | 312元 | |
2024/01/25 | HY-100427 | 甲氧咪草烟 Imazamox | 114311-32-9 | 10mg | 500元 |