儿茶素没食子酸酯
| 中文名称 | 儿茶素没食子酸酯 |
|---|---|
| 中文同义词 | 儿茶素没食子酸;(-)-没食子酸儿茶素酯;(2S,3R)-2-(3,4-二羟苯基)-3,4-二氢-1(2H)-苯并-3,5,7-三醇3-(3,4,5-三羟基苯甲酸);儿茶素没食子酸酯;(-)-儿茶素没食子酸酯;儿茶素没食子酸酯CG;儿茶素没食子酯酸;CATECHIN GALLATE 儿茶素没食子酸 |
| 英文名称 | (-)-CATECHIN GALLATE |
| 英文同义词 | (-)-Catechin gallate(CG);Anti-HCG β, C-Terminal antibody produced in rabbit;Choriogonadotropin subunit β;Chorionic gonadotrophin chain β;ANTI-CG antibody produced in mouse;ECSMSZS;()-Catechin gallate, >=98%;(-)-CG |
| CAS号 | 130405-40-2 |
| 分子式 | C22H18O10 |
| 分子量 | 442.37 |
| EINECS号 | |
| 植物来源 | 茶叶 |
| 相关类别 | 标准品;植物提取物;合成;对照品;中药对照品;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;对照品-杂质对照品;对照品-中药对照品;标准品 -中药标准品;标准品，对照品;试剂盒-Elisa试剂盒;Catechins & Tannins;Aromatics;Chiral Reagents;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals |
| Mol文件 | 130405-40-2.mol |
| 结构式 |  |
儿茶素没食子酸酯 性质
| 熔点 | 248-251 °C (decomp) |
|---|---|
| 沸点 | 861.7±65.0 °C(Predicted) |
| 密度 | 1.80±0.1 g/cm3(Predicted) |
| 储存条件 | 2-8°C |
| 溶解度 | DMSO（微溶）、乙醇（微溶） |
| 形态 | 固体 |
| 酸度系数(pKa) | 7.75±0.25(Predicted) |
| 颜色 | 淡黄色至浅红色 |
| InChIKey | LSHVYAFMTMFKBA-CTNGQTDRSA-N |
| LogP | 2.670 (est) |
|
COX-1
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COX-2
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(-)-Catechin gallate (CG) directly interacts with DNA oligomers and inhibits the activity of COX-1 and COX-2 enzymes, the gene expression of matrix metalloproteinase-9 in macrophage-differentiated HL-60 myeloid leukemia cells, the adipocyte uptake of glucose by the transporter, GLUT4, and the activities of various proteasomes, i.e., the multicatalytic proteases responsible for the degradation of most cellular proteins. The relative cytotoxicities of a 3-day exposure to (-)-Catechin gallate are determined for cancerous CAL27 and HSG cells, immortalized epithelioid S-G cells, and normal HGF-1 gingival fibroblasts. The concentration at which toxicity (P≤0.01) initially occur is 25 μM (-)-Catechin gallate for S-G cells, 50 μM (-)-Catechin gallate for CAL27 cells, 62.5 μM (-)-Catechin gallate for HSG cells and 75 μM (-)-Catechin gallate for HGF-1 fibroblasts. The calculated neutral red (NR 50 ) values for a 3-day exposure to (-)-Catechin gallate are 58 μM for S-G cells, 62 μM for CAL27 cells, 90 μM for HSG cells and 132 μM for HGF-1 fibroblasts.
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/01/25 | HY-N0356 | (-)-Catechin gallate | 1 mg | 1112元 | |
| 2024/01/25 | HY-N0356 | 儿茶素没食子酸酯 (-)-Catechin gallate | 130405-40-2 | 5mg | 1550元 |