亮氨酸脑啡肽
中文名称 | 亮氨酸脑啡肽 |
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中文同义词 | 亮氨酸脑啡肽;N-[N-[N-(N-L-酪氨酰甘氨酰)甘氨酰]-L-苯丙氨酰]-L-亮氨酸;亮氨酸脑啡肽乙酸盐的水合物;亮氨酸脑啡肽(TFA盐);[LEU5]-脑啡肽?, BR;LEU5]-脑啡肽;亮啡肽;醋酸亮氨酸脑啡肽 |
英文名称 | [LEU5]-ENKEPHALIN |
英文同义词 | leucine enkephalin acetate hydrate;(5-LEUCINE)ENKEPHALIN 96+%;L-Tyr-Gly-Gly-L-Phe-L-Leu-OH;Tyr-Gly-Gly-Phe-Leu-OH;Leu-Enkelphalin Tyr-Gly-Gly-Phe-Leu;L-TYR-GLY-GLY-PHE-LEU;LEUCINE-ENKEPHALIN (HUMAN, PORCINE, BOVINE, RAT, MOUSE);LEUCINE-ENKEPHALIN (HUMAN, PORCINE, BOVINE, RAT, MOUSE) H2O |
CAS号 | 58822-25-6 |
分子式 | C28H37N5O7 |
分子量 | 555.62 |
EINECS号 | 261-457-1 |
相关类别 | 多肽;药物多肽;Pepetides;peptides;Peptide;Opioid receptor and opioid-like receptor |
Mol文件 | 58822-25-6.mol |
结构式 |
亮氨酸脑啡肽 性质
熔点 | 130-133 °C |
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比旋光度 | +32.3°(c=9,メタノール) |
沸点 | 998.8±65.0 °C(Predicted) |
密度 | 1.274±0.06 g/cm3(Predicted) |
储存条件 | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
溶解度 | 水中≥54.6 mg/mL;乙醇中≥54.8 mg/mL; DMSO 中≥55.6 mg/mL |
形态 | 冻干粉 |
酸度系数(pKa) | 3.40±0.10(Predicted) |
水溶解性 | Soluble in water (1 mg/ml ). |
序列 | H-Tyr-Gly-Gly-Phe-Leu-OH |
Human Endogenous Metabolite
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Enkephalins (met- , leu-enkephalin, and enkephalin 8) and dynorphins are two classes of opioid peptides found in the spinal dorsal horn. Mu, delta, and kappa are three major subtypes of opioid receptors. Enkephalins are putative endogenous ligands for delta opioid receptors, and dynorphins are endogenous ligands for the kappa opioid receptors. Three receptor types resembling the vertebrate δ- and κ-type opioid receptors have been characterized pharmacologically in nervous tissues (e.g. K i =18.9 nM for Leu-enkephalin) and localized by autoradiography at CHH terminals in the SG of C. maenas .Leucine-enkephalin is a pentapeptides with morphine like properties, naturally present in mammalian brain.
纯度(HPLC) ≥98.0%
醋酸根含量5.0%~12.0%
水分含量≤8.0%
肽含量≥80.0%
提供商 | 语言 |
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英文
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更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024/01/25 | HY-P0288 | [Leu5]-Enkephalin | 5 mg | 343元 | |
2024/01/25 | HY-P0288 | 亮氨酸脑啡肽 [Leu5]-Enkephalin | 58822-25-6 | 10mg | 550元 |