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Technical Data Sheet BUTEIN

Compound Information
Product Name: BUTEIN
CAS No.: 487-52-5
Molecular Formula: C15H12O5
Molecular Weight: 272.25
Storage: Store at ≤-4 °C
Revision Date: 2026-04-15
Analytical Information
Tests Specifications
Description Butein is a cAMP-specific PDE inhibitor with an IC50 of 10.4 μM for PDE4. Butein is a specific protein tyrosine kinase inhibitor with IC50s of 16 and 65 μM for EGFR and p60c-src in HepG2 cells. Butein sensitizes HeLa cells to Cisplatin through AKT and ERK
Form solid
Color yellow
Solubility DMSO: >50 mg/mL
Melting Point 216°C
Purity by HPLC ≥ 98%
¹H NMR Pass test
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