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Technical Data Sheet RO3280

Compound Information
Product Name: RO3280
CAS No.: 1062243-51-9
Molecular Formula: C27H35F2N7O3
Molecular Weight: 543.61
Storage: Powder -20°C 3 years; 4°C 2 years
In solvent -80°C 6 months; -20°C 1 month
Revision Date: 2026-04-15
Analytical Information
Tests Specifications
Description RO3280 is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1) with IC50 of 3 nM.
Form solid
Color Off-white to yellow
Solubility ≥27.2 mg/mL in DMSO; insoluble in H2O; ≥24.75 mg/mL in EtOH
Purity >99%
NMR Pass test
Disclaimer: This information relates only to the specific material designated and may not be valid for such material used in combination with anyother materials or in any other process. Such information is to be the best of the company's knowledge and believed accurate and reliable as of thedate indicated. However, no representation, warranty or guarantee of any kind, express or implied, is made as to its accuracy, reliability orcompleteness and we assume no responsibility for any loss, damage or expense, direct or consequential, arising out of use. It is the user'sresponsibility to satisfy himself as to the suitableness & completeness of such information for his own particular use.
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