| Identification | Back Directory | [Name]
20-BETA-DIHYDROCORTISOL | [CAS]
116-58-5 | [Synonyms]
20β-Dihydrocortisol
202-Dihydrocortisol
20β-Dihydrocortisol
20beta-hydroxycortisol
20-BETA-DIHYDROCORTISOL
REICHSTEIN'S SUBSTANCE 'E'
REICHSTEIN'S COMPOUND ''E''
4-pregnene-11B,17A,20B,21-tetrol-3-one
4-Pregnene-11β,17α,20β,21-tetrol-3-one
11β,17α,20β,21-Tetrahydroxy-4-pregnen-3-one
4-PREGNEN-11-BETA, 17,20-BETA, 21-TETROL-3-ONE
4-PREGNEN-11BETA,17ALPHA,20BETA,21-TETROL-3-ONE
11B,17ALPHA,20B,21-Tetrahydroxy-4-pregnen-3-one
4-pregnene-11beta,17alpha,20beta,21-tetrol-3-one
Pregn-4-en-3-one, 11,17,20,21-tetrahydroxy-, (11β,20R)-
11-beta,17-alpha-20-beta,21-tetrahydroxypregn-4-en-3-one
(8S,9S,10R,11S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-11,17-dihydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one | [Molecular Formula]
C21H32O5 | [MDL Number]
MFCD00151468 | [MOL File]
116-58-5.mol | [Molecular Weight]
364.48 |
| Chemical Properties | Back Directory | [Melting point ]
125°C (rough estimate) | [Boiling point ]
415.66°C (rough estimate) | [density ]
1.0666 (rough estimate) | [refractive index ]
1.6120 (estimate) | [storage temp. ]
Refrigerator | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
20β-Dihydrocortisol could be used as a potential non invasive diagnostic test of transmissible spongiform encephalopaties. 20β-Dihydrocortisol is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism. | [Definition]
ChEBI: 20beta-dihydrocortisol is a 17alpha-hydroxy-C21-steroid that is cortisol in which the 20-oxo group has been reduced to a hydroxy group. It is a metabolite of cortisol identified in the urine of horses and humans, and its urinary excretion is increased in obesity. It has a role as a human urinary metabolite and a mammalian metabolite. It is a 21-hydroxy steroid, a 3-oxo-Delta(4) steroid, a 20-hydroxy steroid, an 11beta-hydroxy steroid and a 17alpha-hydroxy-C21-steroid. It is functionally related to a cortisol. |
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