| Identification | Back Directory | [Name]
21-HYDROXYPREGNENOLONE | [CAS]
1164-98-3 | [Synonyms]
C05485
21-HYDROXYPREGNOLONE
21-HYDROXYPREGNENOLONE
5-Pregnene-3β,21-diol-20-one
5-PREGNEN-3BETA,21-DIOL-20-ONE
5-PREGNENE-3-BETA,21-DIOL-20-ONE
3β,21-Dihydroxy-5-pregnen-20-one
3BETA,21-DIHYDROXY-5-PREGNEN-20-ONE
Pregn-5-en-20-one, 3,21-dihydroxy-, (3β)-
2-hydroxy-1-(3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethanone
2-hydroxy-1-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone | [Molecular Formula]
C21H32O3 | [MDL Number]
MFCD00046238 | [MOL File]
1164-98-3.mol | [Molecular Weight]
332.48 |
| Chemical Properties | Back Directory | [Melting point ]
155-167°C | [Boiling point ]
483.4±45.0 °C(Predicted) | [density ]
1.15±0.1 g/cm3(Predicted) | [storage temp. ]
Refrigerator, Under inert atmosphere | [solubility ]
Chloroform (Sparingly), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
12.98±0.10(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
21-Hydroxypregnenolone, is a hydroxylated metabolite of Pregnenolone (P712200), which is a GABAA antagonist and increases neurogenesis in the hippocampus. It is a modulator of cytochrome P 450-3A. | [Definition]
ChEBI: 21-hydroxypregnenolone is a hydroxypregnenolone that is pregnenolone which has been substituted by a hydroxy group at position 21. It has a role as a mouse metabolite. It is a hydroxypregnenolone, a 21-hydroxy steroid and a primary alpha-hydroxy ketone. |
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