ChemicalBook--->CAS DataBase List--->134865-74-0

134865-74-0

134865-74-0 Structure

134865-74-0 Structure
IdentificationBack Directory
[Name]

4-P-PDOT
[CAS]

134865-74-0
[Synonyms]

AH-024
4-P-PDOT
4-PHENYL-2-PROPIONAMIDOTETRALIN
N-(4-phenyl-1,2,3,4-tetrahydronaphthalen-2-yl)propanamide
N-(4-Phenyl-1,2,3,4-tetrahydronaphthalen-2-yl)propionamide
Propanamide, N-(1,2,3,4-tetrahydro-4-phenyl-2-naphthalenyl)-
4-P-PDOT; 4PPDOT; 4P-PDOT; AH-024; 4-PHENYL-2- PROPIONAMIDOTETRALIN.
[Molecular Formula]

C19H21NO
[MDL Number]

MFCD00901545
[MOL File]

134865-74-0.mol
[Molecular Weight]

279.38
Chemical PropertiesBack Directory
[Melting point ]

166 °C
[Boiling point ]

480.1±45.0 °C(Predicted)
[density ]

1.11±0.1 g/cm3(Predicted)
[storage temp. ]

Store at RT
[solubility ]

Soluble in DMSO > 10 mM
[form ]

powder
[pka]

15.87±0.40(Predicted)
[color ]

white to beige
Safety DataBack Directory
[RTECS ]

TX1498350
[HS Code ]

2924.29.7790
Hazard InformationBack Directory
[Uses]

4-P-PDOT is a MT2 melatonin receptor ligand.
[Definition]

ChEBI: N-(4-phenyl-1,2,3,4-tetrahydronaphthalen-2-yl)propanamide is a member of tetralins.
[Biological Activity]

Melatonin receptor antagonist, >300-fold selective for the MT 2 (vs MT 1 ) subtype.
[Biochem/physiol Actions]

4-P-PDOT is a slelctive MT2 melatonin receptor antagonist 300 fold selective for MT2 (MEL-1B-R) vs MT1 (MEL-1A-R) melatonin receptor subtype.
Spectrum DetailBack Directory
[Spectrum Detail]

4-P-PDOT(134865-74-0)1HNMR
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