| Identification | Back Directory | [Name]
42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin | [CAS]
143030-02-8 | [Synonyms]
Rapamycin Impurity 32
42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin
Rapamycin, 42-O-[(1,1-dimethylethyl)dimethylsilyl]-
Clobetasone Butyrate Impurity 9 (Clobetasone Butyrate EP Impurity I) | [Molecular Formula]
C57H93NO13Si | [MOL File]
143030-02-8.mol | [Molecular Weight]
1028.45 |
| Chemical Properties | Back Directory | [Boiling point ]
977.0±75.0 °C(Predicted) | [density ]
1.12±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
Dichloromethane, Methanol | [form ]
Solid | [pka]
10.40±0.70(Predicted) | [color ]
White |
| Hazard Information | Back Directory | [Uses]
42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin is an intermediate in the synthesis of 8-O-Methyl-rapamycin which is a derivative of Rapamycin (R124000), a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. |
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| Company Name: |
Energy Chemical
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021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
guoyungurui
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18162595016 |
| Website: |
www.chemicalbook.com/supplier/25521782/ |
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