| Identification | More | [Name]
3,4-Methylenedioxy-beta-nitrostyrene | [CAS]
1485-00-3 | [Synonyms]
1-(3,4-METHYLENEDIOXYPHENYL) 2-NITROETHENE
3,4-METHYLENEDIOXY-BETA-NITROSTYRENE
3,4-METHYLENEDIOXY-B-NITROSTYRENE
3,4-METHYLENEDIOXYNITROSTYRENE
5-[(E)-2-NITROVINYL]-1,3-BENZODIOXOLE
AKOS BBS-00006781
TIMTEC-BB SBB007833
-(2-Nitrovinyl)-1,3-benzodioxole
-(2-Nitrovinyl)-3,4-methylenedioxybenzene
,4-(Methylenedioxy)-b-nitrostyrene
,4-Methylenedioxy-1-(2-nitrovinyl)benzene
1,3-Benzodioxole, 5-(2-nitroethenyl)-
1,3-Benzodioxole, 5-nitrovinyl-
3,4-methylenedioxy-beta-nitro-styren
3,4-Methylenedioxy-omega-nitrostyrene
5-[(E)-2-Nitroethenyl]-1,3-benzodioxole
5-nitrovinyl-3-benzodioxole
Benzene, 2-nitroethenyl, 3,4-methylenedioxy
Ethene,-1-(3,4-methylendioxyphenyl)-2-nitro-
Styrene, 3,4-methylenedioxy-beta-nitro- | [EINECS(EC#)]
622-830-8 | [Molecular Formula]
C9H7NO4 | [MDL Number]
MFCD00014575 | [Molecular Weight]
193.16 | [MOL File]
1485-00-3.mol |
| Chemical Properties | Back Directory | [Appearance]
yellow powder | [Melting point ]
159-163 °C | [Boiling point ]
329.36°C (rough estimate) | [density ]
1.4058 (rough estimate) | [refractive index ]
1.5200 (estimate) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Soluble in DMSO (up to 50 mg/ml). | [form ]
Yellow to brown solid | [color ]
Yellow | [Sensitive ]
Light Sensitive | [BRN ]
192350 | [Stability:]
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. | [CAS DataBase Reference]
1485-00-3(CAS DataBase Reference) | [NIST Chemistry Reference]
3,4-Methylenedioxy-«beta»-nitrostyrene(1485-00-3) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi,T | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R22:Harmful if swallowed.
R25:Toxic if swallowed. | [Safety Statements ]
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2811 6.1/PG 3 | [RTECS ]
WL5270000 | [HS Code ]
29329990 |
| Hazard Information | Back Directory | [Description]
MDBN (1485-00-3) is an irreversible inhibitor of p97 (IC50 < 10 μM). Cell permeable. | [Chemical Properties]
yellow powder | [Uses]
MDBN is a Src and Syk kinase inhibitor that prevents phosphorylation and cytoskeletal association of GPIIb/IIIa and talin. | [Biological Activity]
Selective inhibitor of Src and Syk tyrosine kinases. Displays antiaggregative activity via inhibition of GPIIb/IIIa activation (IC 50 = 12.7 μ M for thrombin-induced platelet aggregation). Exhibits no effects on Ca 2+ -dependent enzymes, PKC or arachidonic acid metabolism. | [References]
1) Chou et al. (2011), Quantitative cell-based protein degradation assays to identify and classify drugs that target the ubiquitin-proteasome system; J. Biol. Chem., 286 16546 |
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