| Identification | More | [Name]
3-Bromo-2-fluorobenzoic acid | [CAS]
161957-56-8 | [Synonyms]
3-BROMO-2-FLUOROBENZOIC ACID
BUTTPARK 14\01-30
3-Bromo-2-fluorobenzoic
3-Bromo-2-fluorobenzoic acid 97%+ | [Molecular Formula]
C7H4BrFO2 | [MDL Number]
MFCD00665763 | [Molecular Weight]
219.01 | [MOL File]
161957-56-8.mol |
| Chemical Properties | Back Directory | [Melting point ]
168 °C | [Boiling point ]
298.2±25.0 °C(Predicted) | [density ]
1.789±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
powder to crystal | [pka]
2.88±0.10(Predicted) | [color ]
White to Light yellow | [InChIKey]
UVKURTLVTLRSSM-UHFFFAOYSA-N | [CAS DataBase Reference]
161957-56-8(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
Off-white powder | [Uses]
3-Bromo-2-fluorobenzoic acid is used as a reagent to synthesize Dabrafenib, an inhibitor of BRAF kinase that is used to treat BRAF V600-mutation positive carcinoma. BRAF is a gene that mediates cell growth and is activated by mutations caused by cancer. 3-Bromo-2-fluorobenzoic acid is also used as a reagent to prepare Alkynlphenoxyacetic acid receptor agonists, compounds that can be potentially used for the treatment of allergic inflammatory diseases (such as allergic rhinitis). |
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