ChemicalBook--->CAS DataBase List--->31252-42-3

31252-42-3

31252-42-3 Structure

31252-42-3 Structure
IdentificationMore
[Name]

4-BENZYLPIPERIDINE
[CAS]

31252-42-3
[Synonyms]

4-BENZYLPIPERIDINE
4-(PHENYLMETHYL)PIPERIDINE
AKOS BBS-00003617
ALPHA-(4-PIPERIDYL)TOLUENE
LABOTEST-BB LTBB000752
PHENYL(4-PIPERIDYL)METHANE
4-(phenylmethyl)-piperidin
4-benzyl-piperidin
Piperidine, 4-(phenylmethyl)-
Piperidine, 4-benzyl-
4-Benzylpiperidine99%
[EINECS(EC#)]

250-535-0
[Molecular Formula]

C12H17N
[MDL Number]

MFCD00006006
[Molecular Weight]

175.27
[MOL File]

31252-42-3.mol
Chemical PropertiesBack Directory
[Appearance]

CLEAR COLOURLESS TO YELLOW VISCOUS LIQUID
[Melting point ]

6-7 °C (lit.)
[Boiling point ]

279 °C (lit.)
[density ]

0.997 g/mL at 25 °C(lit.)
[refractive index ]

n20/D 1.537(lit.)
[Fp ]

>230 °F
[storage temp. ]

Store below +30°C.
[form ]

Viscous Liquid
[pka]

10.58±0.10(Predicted)
[color ]

Clear colorless to yellow
[BRN ]

132339
[CAS DataBase Reference]

31252-42-3(CAS DataBase Reference)
[EPA Substance Registry System]

Piperidine, 4-(phenylmethyl)- (31252-42-3)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
[WGK Germany ]

3
[RTECS ]

TM4728000
[Hazard Note ]

Irritant
[TSCA ]

Yes
[HazardClass ]

IRRITANT
[HS Code ]

29333990
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Sodium hydroxide-->Hydrochloric acid-->Tetrahydrofuran-->Dichloromethane-->Thionyl chloride-->Potassium carbonate-->Potassium hydroxide-->Acetic anhydride-->Benzene-->Lithium Aluminum Hydride-->Aluminum chloride-->Sodium borohydride-->Isopropyl alcohol-->Trifluoroacetic acid-->Hydrazine hydrate-->Calcium chloride-->1,2-Dichloroethane-->Diisopropyl ether-->Diethylene glycol-->Isonipecotic acid-->Triethylsilane
Hazard InformationBack Directory
[Chemical Properties]

CLEAR COLOURLESS TO YELLOW VISCOUS LIQUID
[Uses]

4-Benzylpiperidine was studied as acid corrosion inhibitor for iron. It was also used to study potential utility of dopamine-welective releaser as a treatment for cocaine dependence. In an assay of cocaine discrimination, 4-Benzylpiperidine had the most rapid onset and shortest duration of action.
[Uses]

Reactant for synthesis of:
Antiproliferatives
GABA uptake inhibitors
Pyridines
Histamine H3 antagonists
Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer′s and neuronal vascular diseases
Antiserotoninergic, antiplatelet, hemorheologic, antiarrythmic and antioxidant molecules via nucleophilic substitution
[Application]

Reactant for synthesis of:
Antiproliferatives
GABA uptake inhibitors
Pyridines
Histamine H3 antagonists
Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer′s and neuronal vascular diseases
Antiserotoninergic, antiplatelet, hemorheologic, antiarrythmic and antioxidant molecules via nucleophilic substitution
[Preparation]

4-Benzylpiperidine can be prepared by reacting 4-cyanopyridine with toluene. Catalytic hydrogenation of the pyridine ring then completes the synthesis.
[Synthesis Reference(s)]

Synthesis, p. 741, 1980 DOI: 10.1055/s-1980-29196
[General Description]

4-Benzylpiperidine is dopamine-selective releaser. It is a potential candidate for treatments for cocaine dependence.
[Biochem/physiol Actions]

4-Benzylpiperidine inhibits the activity of rat brain monoamine oxidase-A and -B.
Spectrum DetailBack Directory
[Spectrum Detail]

4-BENZYLPIPERIDINE(31252-42-3)MS
4-BENZYLPIPERIDINE(31252-42-3)1HNMR
4-BENZYLPIPERIDINE(31252-42-3)13CNMR
4-BENZYLPIPERIDINE(31252-42-3)IR1
4-BENZYLPIPERIDINE(31252-42-3)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

4-Benzylpiperidine, 98%(31252-42-3)
[Alfa Aesar]

4-Benzylpiperidine, 98%(31252-42-3)
[Sigma Aldrich]

31252-42-3(sigmaaldrich)
[TCI AMERICA]

4-Benzylpiperidine,>99.0%(GC)(31252-42-3)
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