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342613-14-3

342613-14-3 Structure

342613-14-3 Structure
IdentificationBack Directory
[Name]

Docetaxel 2’-tert-Butylsimethylsilyl Ether
[CAS]

342613-14-3
[Synonyms]

Paclitaxel Impurity 107
Docetaxel 2’-tert-Butylsimethylsilyl Ether
Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]be...
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-9-((4R)-4-((S)-((Tert-butoxycarbonyl)amino)(phenyl)methyl)-2-(tert-butyl)-2-methyl-5-oxo-1l3,3,2-dioxasilolan-1-yl)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-12b-(prop-1-en-2-yloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate
[Molecular Formula]

C49H67NO14Si
Chemical PropertiesBack Directory
[Boiling point ]

898.5±65.0 °C(Predicted)
[density ]

1.27±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

11.16±0.46(Predicted)
[color ]

White
Hazard InformationBack Directory
[Uses]

Docetaxel 2’-tert-Butylsimethylsilyl Ether is an intermediate in the synthesis of Docetaxel (D494420),a semisynthetic derivative of Paclitaxel(P132500), an antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin.
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