ChemicalBook--->CAS DataBase List--->370586-05-3

370586-05-3

370586-05-3 Structure

370586-05-3 Structure
IdentificationBack Directory
[Name]

CID 797718
[CAS]

370586-05-3
[Synonyms]

CS-1341
CID 797718
CID 797718, >=98%
CID-797718;CID797718
CID 797718, 370586-05-3
9-Hydroxy-1H,2H,3H,4H-chromeno[3,4-b]pyridin-5-one
9-HYDROXY-1,2,3,4-TETRAHYDROCHROMENO[3,4-B]PYRIDIN-5-ONE
9-HYDROXY-3,4-DIHYDRO-1H-CHROMENO[3,4-B]PYRIDIN-5(2H)-ONE
[Molecular Formula]

C12H11NO3
[MDL Number]

MFCD03006523
[MOL File]

370586-05-3.mol
[Molecular Weight]

217.22
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 1 mg/ml
[form ]

A crystalline solid
Hazard InformationBack Directory
[Description]

CID797718 is a protein kinase D1 (PKD1) inhibitor (IC50 = 7 μM). It also inhibits CDK activating kinase (CAK) and polo-like kinase 1 (PLK1) but has no activity at AKT (IC50s = 8.4, 21.9, and >50 μM, respectively). CID797718 inhibits PKD1 activity in LNCaP cells with an IC50 value of 0.21 μM. CID797718 is a byproduct in the synthesis of CID755673 .
[storage]

Store at -20°C
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