| Identification | Back Directory | [Name]
osthenol | [CAS]
484-14-0 | [Synonyms]
NSC 625328
7-Hydroxy-8-prenylcoumarin
7-Hydroxy-8-isopentenyl-2H-1-benzopyran-2-one
7-Hydroxy-8-(3-methyl-2-butenyl)-2H-1-benzopyran-2-one
2H-1-Benzopyran-2-one, 7-hydroxy-8-(3-methyl-2-buten-1-yl)- | [Molecular Formula]
C14H14O3 | [MDL Number]
MFCD03427690 | [MOL File]
484-14-0.mol | [Molecular Weight]
230.26 |
| Chemical Properties | Back Directory | [Melting point ]
89-91 °C | [Boiling point ]
422.8±45.0 °C(Predicted) | [density ]
1.203±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [pka]
8.45±0.20(Predicted) | [LogP]
3.342 (est) |
| Hazard Information | Back Directory | [Chemical Properties]
Soluble in methanol, ethanol, DMSO and other organic solvents, derived from Rhizoma et Radix Notopterygii. | [Definition]
ChEBI: Osthenol is a hydroxycoumarin that is umbelliferone in which the hydrogen at position 8 has been replaced by a prenyl group. It has a role as a plant metabolite and an antifungal agent. It is functionally related to an umbelliferone. | [Biological Activity]
Ostenol (Ostenol), a preacylated coumarin isolated from the dried roots of Ostonia, is a reversible, selective and competitive inhibitor of human monoamine oxidase-A (hMAO-A) (Ki=0.26 μM) . Oshenol has a potential selective inhibitory effect on recombinant hMAO-A with IC50 of 0.74 μM, showing a high selectivity index for hMAO-A and hMAO-B. | [storage]
Store at -20°C |
|
|