| Identification | Back Directory | [Name]
UNCARINE E | [CAS]
5171-37-9 | [Synonyms]
UNCARINE E
ISOPTEROPODINE
7-Isopteropodine
Rhynchophylline E
allo-Isopteropodine
Isopteropodine (20 mg)
Isopteropodine(Uncarine E)
(7S,20α)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester
(7alpha,19alpha,20alpha)-19-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester
methyl (1R,4aR,10aR)-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate
methyl (1R,4aR,10aR)-1-methyl-2'-oxo-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate
(1R,4aR,10aR)-2'-keto-1-methyl-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-indoline]-4-carboxylic acid methyl ester
Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3S,4'aS,5'aS,10'aS)- | [Molecular Formula]
C21H24N2O4 | [MDL Number]
MFCD03788766 | [MOL File]
5171-37-9.mol | [Molecular Weight]
368.43 |
| Chemical Properties | Back Directory | [Melting point ]
209-211 °C | [Boiling point ]
555.2±50.0 °C(Predicted) | [density ]
1.33 | [storage temp. ]
-20°C Freezer | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
13.56±0.60(Predicted) | [color ]
Pale Yellow to Pale Beige |
| Hazard Information | Back Directory | [Description]
This alkaloid occurs in several species of Uncaria and yields colourless crystals
from MeOH. It is laevorotatory with [α]D - 96° (CHCI3). The structure has
been determined by spectroscopic methods. | [Uses]
Isopteropodine is an alkaloid extract from Uncaria Tomentosathat is believed to possess antiproliferative and pro-apoptotic effects. | [Definition]
ChEBI: Uncarine E is a member of indolizines. | [References]
Hart, Johns, Lamberton., Chem. Commun., 87 (1967)
Hemingway, Phillipson., 1. Pharm. Pharmacol., 24, 169P (1972) |
|
| Company Name: |
BioBioPha Co., Ltd.
|
| Tel: |
0871-65217109 13211707573; |
| Website: |
http://www.biobiopha.com |
|