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60117-35-3

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60117-35-3 Structure

60117-35-3 Structure
IdentificationBack Directory
[Name]

ANB-NOS
[CAS]

60117-35-3
[Synonyms]

ANB-NOS
ANB-NOS Crosslinker
5-AZIDO-2-NITROBENZOYLOXYSUCCINIMIDE
N-5-AZIDO-2-NITROBENZOYLOXYSUCCINIMIDE
N-SUCCINIMIDYL 5-AZIDO-2-NITROBENZOATE
N-Succinimidyl 5-Azido-2-nitrobenzoate >
N-hydroxysuccinimidyl-5-azido-2-nitrobenzoate
N-Succinimidyl 5-Azido-2-nitrobenzoate
5-Azido-2-nitrobenzoic Acid N-Succinimidyl Ester
5-Azido-2-nitrobenzoic acid N-hydroxysuccinimide ester
2,5-Pyrrolidinedione, 1-[(5-azido-2-nitrobenzoyl)oxy]-
Benzoic acid,5-azido-2-nitro-, 2,5-dioxo-1-pyrrolidinyl ester
N-(5-Azido-2-nitrobenzoyloxy)succinimide, N-Succinimidyl 5-azido-2-nitrobenzoate
N-(5-Azido-2-nitrobenzoyloxy)succinimide 5-Azido-2-nitrobenzoic Acid N-Succinimidyl Ester ANB-NOS
[Molecular Formula]

C11H7N5O6
[MDL Number]

MFCD00054962
[MOL File]

60117-35-3.mol
[Molecular Weight]

305.2
Chemical PropertiesBack Directory
[Melting point ]

131-133°C
[storage temp. ]

2-8°C
[solubility ]

ethyl acetate: 25 mg/mL
[form ]

powder
[color ]

yellow
[BRN ]

1555224
Safety DataBack Directory
[Safety Statements ]

22-24/25
[WGK Germany ]

3
[F ]

3-8-10
[HS Code ]

29299090
Hazard InformationBack Directory
[Description]

ANB-NOS Crosslinker contains a nitrophenyl azide group and an amine reactive NHS ester group. It is also able to react with nucleophiles.
[Uses]

Anb-Nos Crosslinker can be used for devices implanted in the eyes to treat glaucoma and/or dry eye.
[Uses]

Photoactive, heterobifunctional cross-linking reagent. Typically, initial reaction couples via ester to primary amine by amide bond formation in the pH range 6.5-8.5. Second bonding occurs during UV irradiation (250-350 nm) via reactive nitrene. The latter bonding is rapid and non-specific.
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