| Identification | Back Directory | [Name]
cis-4-Hydroxy-D-proline hydrochloride | [CAS]
77449-94-6 | [Synonyms]
cis-D-Hyp-OH.HCl
H-D-cis-Hyp-OH.HCL
Cis-4-OH-D-pro-OH·HCl
CIS-4-HYDROXY-D-PROLINE HCL
cis-4-Hydro×y-D-proline hydrochloride
cis-4-Hydroxy-D-proline hydrochloride
(2R,4R)-4-hydroxyproline hydrochloride
D-Proline, 4-hydroxy-,hydrochloride (1:1)
Cis-4-hydroxy-D-proline monohydrochloride
(2R,4R)-cis-4-hydroxy-D-proline hydrochloride
cis-4-Hydroxy-D-proline hydrochloride USP/EP/BP
(2R,4R)-4-Hydroxypyrrolidine-2-Carboxylic Acid hydrochlorid
(2R,4R)-4-Hydroxy-pyrrolidine-2-carboxylic acid hydrochloride
cis-4-Hydroxy-D-proline hydrochloride ((2R,4R)-4-Hydroxy-pyrrolidine-2-carboxylic acid hydrochloride) | [EINECS(EC#)]
1592732-453-0 | [Molecular Formula]
C5H10ClNO3 | [MDL Number]
MFCD09749867 | [MOL File]
77449-94-6.mol | [Molecular Weight]
167.591 |
| Chemical Properties | Back Directory | [Melting point ]
114-116 °C | [storage temp. ]
Inert atmosphere,Room Temperature | [InChI]
InChI=1/C5H9NO3.ClH/c7-3-1-4(5(8)9)6-2-3;/h3-4,6-7H,1-2H2,(H,8,9);1H/t3-,4-;/s3 | [InChIKey]
YEJFFQAGTXBSTI-QYDODFSFNA-N | [SMILES]
C(O)(=O)[C@H]1C[C@@H](O)CN1.[H]Cl |&1:3,5,r| |
| Questions And Answer | Back Directory | [Uses]
Cis-4-Hydroxy-D-proline belongs to the class of organic compounds known as proline and derivatives. Proline and derivatives are compounds containing proline or a derivative thereof resulting from a reaction of proline at the amino group or the carboxyl group, or from the replacement of any hydrogen of glycine by a heteroatom. cis-4-Hydroxy-D-proline is a substrate that may be used to study the specificity and kinetics of D-alanine dehydrogenase.
| [Synthetic Application]
Cis-4-Hydroxy-D-proline may be used as a starting material for the 13-step synthesis of new conformationally restricted PNA adenine monomer and the synthesis of N-Benzyl pyrrolidinyl sordaricin derivatives. Cis-4-Hydroxy-D-proline is a substrate that may be used to study the specificity and kinetics of D-alanine dehydrogenase. Cis-4-Hydroxy-D-proline may be used to analyze the substrate specificity of amino acid transporter PAT1.
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