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ChemicalBook--->CAS DataBase List--->87402-88-8

87402-88-8

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87402-88-8 Structure

87402-88-8 Structure
IdentificationBack Directory
[Name]

(-)-Denudatin B
[CAS]

87402-88-8
[Synonyms]

C10554
(-)-Denudatin B
(-)-Denudatin B
(2S,3R,3aS)-2-(3,4-dimethoxyphenyl)-3a-methoxy-3-methyl-5-prop-2-enyl-2,3-dihydrobenzofuran-6-one
[Molecular Formula]

C21H24O5
[MOL File]

87402-88-8.mol
[Molecular Weight]

356.41
Chemical PropertiesBack Directory
[storage temp. ]

4°C, away from moisture and light
Hazard InformationBack Directory
[Definition]

ChEBI: Denudatin B is a member of benzofurans.
[Biological Activity]

(-)-Denudatin B is an antiplatelet agent. (-)-Denudatin B relaxed vascular smooth muscle by inhibiting the Ca2+ influx through voltage-gated and receptor-operated Ca2+ channels[1]. And (-)-Denudatin B has nonspecific antiplatelet action
[References]

[1]. Yu SM,et al. Vasorelaxing effect in rat thoracic aorta caused by denudatin B, isolated from the Chinese herb, magnolia fargesii. Eur J Pharmacol. 1990;187(1):39-47. [2]. Teng CM, et al. Inhibition of thrombin- and collagen-induced phosphoinositides breakdown in rabbit platelets by a PAF antagonist--denudatin B, an isomer of kadsurenone. Thromb Res. 1990;59(1):121-130.
Spectrum DetailBack Directory
[Spectrum Detail]

(-)-Denudatin B(87402-88-8)1HNMR
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