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6893-26-1

中文名称 D-谷氨酸
英文名称 D(-)-Glutamic acid
CAS 6893-26-1
EINECS 编号 230-000-8
分子式 C5H9NO4
MDL 编号 MFCD00063112
分子量 147.13
MOL 文件 6893-26-1.mol
更新日期 2024/05/29 16:47:04
6893-26-1 结构式 6893-26-1 结构式

基本信息

中文别名
D-谷氨酸
D-麸胺酸
D-2-氨基戊二酸
D-麸氨酸
D-麸质酸
D-谷氨酸(试剂)
D-Α-氨基戊二酸,D-Α-AMINOPENTANEDIOIC ACID
D-谷氨酸/Α-氨基戊二酸
D-谷氨酸, 99+%
英文别名
-GLU
NSC 77686
H-D-GLU-OH
d-glutamic
D-Glutamate
d-glutamicaci
D-Glutaminsure
D-GLUTAMIC ACID
(R)-GLUTAMIC ACID
GLUTAMIC ACID, D-
D-Glutaminic acid
(2R)-GlutaMic Acid
D-GLUCURONOLACTONE
D-(-)-GLUTAMIC ACID
D-GLUTAMIC ACID, 99+%
D-GlutaMic acid, 95+%
D-α-AMinoglutaric acid
D-2-AMINOGLUTARIC ACID
(R)-2-AMINOGLUTARIC ACID
D-GLUTAMIC ACID extrapure
(2R)-2-Aminoglutaric acid
D-ALPHA-AMINOGLUTARIC ACID
D-2-AMINOPENTANEDIOIC ACID
[R]-2-AMINOPENTANEDIOIC ACID
D(-)-GlutaMic acid, 99+% 5GR
D(-)-GlutaMic acid, 99+% 25GR
(2R)-2-aminopentanedioic acid
D-1-AMinopropane-1,3-dicarboxylic acid
(R)-1-AMINOPROPANE-1,3-DICARBOXYLIC ACID
(R)-2-Aminoglutaric acid, (R)-2-Aminopentanedioic acid, D-Glu, R-(-)-1-Aminopropane-1,3-dicarboxylic acid
所属类别
生物化学品: 生化试剂: 氨基酸及其衍生物

物理化学性质

外观性状白色结晶或结晶性粉末;溶于水,微溶于乙醇,不溶于乙醚;比旋光度[α]20D-30.5°(0.5-2mg/ml,6mol/L HCl),LD50(人,静脉) 117mg/kg。
熔点200-202 °C (subl.)(lit.)
熔点200-202 °C (subl.)(lit.)
比旋光度-31.3 º (c=10, 2 N HCl)
沸点267.21°C (rough estimate)
密度1.5380
折射率1.4210 (estimate)
储存条件Keep in dark place,Sealed in dry,Room Temperature
储存条件Store at RT.
溶解度可微溶于水
酸度系数(pKa)pK1:2.162(+1);pK2:4.272(0);pK3:9.358(-1) (25°C)
形态粉末
颜色白色至灰白色
水溶解性7 g/L (20 ºC)
Merck14,4469
BRN1723800
InChIKeyWHUUTDBJXJRKMK-GSVOUGTGSA-N
LogP-0.969 (est)
NIST化学物质信息D-Glutamic acid(6893-26-1)
EPA化学物质信息D-Glutamic acid (6893-26-1)

安全数据

危险性符号(GHS)
GHS07
警示词警告
危险性描述H315-H319
危险品标志Xi
危险类别码36/37/38
安全说明24/25-36-26
安全说明S24/25
WGK Germany3
WGK Germany3
TSCAYes
海关编码29224210

应用领域

用途一
用于生化研究。
用途二
氨基酸类药。
参考质量标准
比旋光度[α]20D-31°--33°;纸层析合格。

制备方法

方法一
以乙酰-DL-谷氨酸为原料,经酰化酶处理后去L-型,精制、干燥得产品。

化学品安全说明书(MSDS)

D-谷氨酸价格(试剂级)
报价日期产品编号产品名称CAS号包装价格
2024/04/30A14191D-谷氨酸, 99+%
D-Glutamic acid, 99+%
6893-26-15g451元
2024/04/30A14191D-谷氨酸, 99+%
D-Glutamic acid, 99+%
6893-26-125g1407元
2024/04/30A14191D-谷氨酸, 99+%
D-Glutamic acid, 99+%
6893-26-1100g4119元

常见问题列表

生物活性
D-glutamic acid是L-glutamic acid的对映异构体,广泛用于药物和食品中。
靶点

Human Endogenous Metabolite

体外研究

Various d-amino acids, such as D-serine, D-aspartic acid (D-Asp), and D-glutamic acid (D-Glu) are widely found in mammals including human beings and they are now thought to be the candidates of novel physiologically active substances and/or biomarkers. D-[Asp/Glu] (4 mg/mL) inhibits IgE binding (75%) to peanuts while D-Glu, D-Asp has no inhibitory effect. IgE is specific for D-[Asp/Glu] and may have the potential for removing IgE or reducing IgE binding to peanut allergens.

体内研究

D-glutamic acid is currently paid attention as a modulator of neuronal transmission and hormonal secretion. It is metabolized only by D-aspartate oxidase in mammals. After intraperitoneal injection, L-glutamate is catabolized via a-ketoglutarate, whereas D-glutamate is converted to n-pyrrolidone carboxylic acid. Carbon 2 of both D- and L-glutamate is converted in the cecum to the methyl carbon of acetate. Both rat liver and kidney catalyze the conversion of D-glutamic acid to n-pyrrolidone carboxylic acid.

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