地莫西泮
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- CAS号:
- 963-39-3
- 英文名:
- Demoxepam
- 英文别名:
- ro5-2092;NSC 4607;Ro 5-2092;NSC-46077;NSC-46007;Demoxepam;NSC 169898;ro5-2092lactam;Ro 5-2092 lactam;Demoxepam solution
- 中文名:
- 地莫西泮
- 中文别名:
- 地莫西泮;嘧莫昔芬;去氧安定;氯氮草杂质A;氯氮卓杂质A;奥沙西泮杂质E;氯氮杂EP杂质A;奥沙西泮EP杂质E;氯氮草相关物质A USP标准品;奥沙西泮杂质5(奥沙西泮EP杂质E)
- CBNumber:
- CB4501398
- 分子式:
- C15H11ClN2O2
- 分子量:
- 286.71
- MOL File:
- 963-39-3.mol
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地莫西泮化学性质
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熔点:
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235-236 °C (decomp)
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密度:
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1.40±0.1 g/cm3(Predicted)
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闪点:
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2℃
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储存条件:
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-20°C
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溶解度:
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Chloroform (Slightly), Methanol (Slightly)
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形态:
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Solid
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酸度系数(pKa):
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pKa 4.5 (Uncertain)
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颜色:
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White to Pale Yellow
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NIST化学物质信息:
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Demoxepam(963-39-3)
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地莫西泮性质、用途与生产工艺
Demoxepam 是 Chlordiazepoxide 的主要代谢产物。Demoxepam 对癌细胞系表现出细胞毒性活性。 Demoxepam 具有抗惊厥和抗焦虑作用。
化学性质
结晶（二氯甲烷/己烷）。熔点 239-241℃ 。
用途
安宁、舒宁（去甲羟安定）的中间体。
生产方法
用对硝基氯苯与苄基腈在乙醇中于氢氧化钠参与下环合，生成5-氯-3-苯基苯并异噁唑，然后以铁粉-盐酸还原并开环得2-氨基-5-氯二苯甲酮，进而以盐酸羟胺肟化得2-氨基-5-氯二苯酮肟。将后者与氯乙酰氯环合得6-氯-2-氯甲基-4-苯基喹唑啉-3-氧化物，再在氢氧化钠作用下扩环制得该品。
地莫西泮
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/01/25 | HY-136591 | 地莫西泮
Demoxepam | 963-39-3 | 1mg | 3200元 |
地莫西泮
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963-39-3, 地莫西泮 相关搜索:
- Pharmaceuticals
- Metabolites & Impurities
- Intermediates & Fine Chemicals
- Heterocycles
- Aromatics
- 奥沙西泮杂质5(奥沙西泮EP杂质E)
- 奥沙西泮杂质E
- 去氧安定
- 氯氮杂EP杂质A
- 奥沙西泮EP杂质E
- 氯氮卓杂质A
- 氯氮卓杂质A(EP)/奥沙西泮杂质E(EP)
- 嘧莫昔芬
- 氯氮草相关物质A USP标准品
- 7-氯-1,3-二氢-5-苯基-2H-1,4-苯并二氮杂-2-酮4-氧化物
- 地莫西泮
- 7-氯-5-苯基-1, 3-二氢-2H-1, 4-苯并二氮杂卓-2-酮-4-氧化物
- 氯氮草杂质A
- 963-39-3
- Chlordiazepoxide EP Impurity A
Chlordiazepoxide Related Compound A (7-Chloro-1,3-dihydro-5- phenyl-2H-1,4-benzodiazepin-2-one 4-Oxide)
- Chlordiazepoxide Hydrochloride EP Impurity A
- Chlordiazepoxide USP Related Compound A
- 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2
-one-4-oxide [cas#963-39-3]
- Oxazepam Impurity 5 (Oxazepam EP Impurity E)
- 7-chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazpine-2-one-4-o...
- Chlordiazepoxide EP impurity A/ Chlordiazepoxide Related Compund A (Demoxepam)
- Chlordiazepoxide EP Impurity A
- Oxazepam EP Impurity E
- Demoxepam solution
- Chlordiazepoxide Related CoMpound A
- 7-chloro-5-phenyl-1, 3-dihydro-2H-1, 4-benzodiazpine-2-one-4-oxide
- Nordiazepam 4-oxide
- 7-Chloro-5-phenyl-1,5-dihydro-2H-1,4-benzodiazepin-2-one 4-oxide
- NSC 4607
- NSC 169898
- 7-Chloro-2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one 4-oxide
- 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one 4-oxide
5-Phenyl-7-chloro-3H-1,4-benzodiazepin-2(1H)-one 4-oxide
- Chlordiazepoxide Related Compound A (25 mg) (7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one 4-Oxide)
- 7-chloro-4-hydroxy-5-phenyl-3H-1,4-benzodiazepin-2-one
- Demoxepam
- 7-Chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepine-2-one 4-oxide
- 1,3-Dihydro-5-phenyl-7-chloro-2H-1,4-benzodiazepin-2-one-4-oxide(diazepinoneN-oxide)
- 7-chloro-2-oxo-5-phenyl-1.3-dihydro-2H-1.4-benzoiazepine-4-oxide
- 7-Chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one 4-oxide
- 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-one N-oxide
- 7-chloro-1,3-dihydro-5-phenyl-2h-1,4-benzodiazepin-2-one-4-oxide
- 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-ben-zodiazepin-2-one4-oxide
- 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one-4-oxid
- 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one 4-oxide
- 4-benzodiazepin-2-one,7-chloro-1,3-dihydro-5-phenyl-2h-4-oxide
- 4-benzodiazepin-2-one,1,3-dihydro-7-chloro-5-phenyl-2h-4-oxide
- 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-phenyl-, 4-oxide
- 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-phenyl-, 4-oxide
- 1,3-dihydro-7-chloro-5-phenyl-2h-1,4-benzodiazepin-2-one4-oxide
- CHLORDIAZEPOXIDE RELATED COMPOUND A (25 MG) (7-CHLORO-1,3-DIHYDRO-5-PHENYL-2H-1,4-BENZODIAZEPIN-2-ONE 4-OXIDE)
- ro5-2092lactam
- ro5-2092
- Ro 5-2092 lactam