rac erythro-9-(2-Hydroxy-3-nonyl)adenine, Hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
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Verwenden
A potent inhibitor of phosphodiesterase II (PDE II) (IC50=800nM). Does ot inhibit other PDE isozymes (IC50>100uM). Inhibits the retrograde transport motor, dynein. Also inhibits adenosine deaminase (Ki=4nM).
Definition
ChEBI: A hydrochloride salt obtained by reaction of (2R,3S)-EHNA with one equivalent of hydrochloric acid. Selective inhibitor of cGMP-stimulated phosphodiesterase (PDE2) (IC50 = 0.8 - 4
M). Also a potent inhibitor of adenosine deaminase.
rac erythro-9-(2-Hydroxy-3-nonyl)adenine, Hydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
